The functional impact of missense germline variants was predicted using MetaSVM ensemble algorithm28 and annotation by ClinVar database when available31. We considered a missense variant high-functional impact if classified as Deleterious by MetaSVM or listed as Pathogenic/Likely-Pathogenic in ClinVar....
In contrast to the ADI-R and the PL-ADOS, Figure 1 shows that clinicians rarely (2 in 172 cases or 1%) classified children as having autism who had not been classified in the same way by 1 of the other measures. On the other hand, clinicians relatively frequently (26 in 172 cases or...
performance IQ76. On the other hand, schizophrenia is a highly heritable mental disorder that exhibits functional dysconnectivity throughout the brain77. AD was causally associated with FC-BAG with nominal significance [risk effect for per unit increase;Pvalue = 4.43 × 10−2, OR (9...
(2018). 5.1 Introduction 69 In this chapter, I show how to calculate some of these implicit age-specific properties from any stage-classified model. The trick is to formulate the life cycle as a Markov chain, and to generalize the "life" cycle to include death as a stage. Because death...
Perivascular spaces can be classified according to the location of blood vessels, as well as according to morphology. The two most common types are the single follicle type that is an isolated and round-like cystic structure and the local cluster type constituted by multiple strips and lines. ...
Perivascular spaces can be classified according to the location of blood vessels, as well as according to morphology. The two most common types are the single follicle type that is an isolated and round-like cystic structure and the local cluster type constituted by multiple strips and lines. ...
eCRF was calculated with the age- and sex-specific algorithms, and classified as lower (lowest 25%), middle (middle 50%) and upper (highest 25%). ... I Lee,J Kim,H Kang - 《International Journal of Environmental Research & Public Health》 被引量: 0发表: 2020年 Inter- and intra-spe...
Data quality is of special concern when it comes to survey research in nursing homes. Very little is known about specifics of cognitively impaired elderly in responding to survey questions. This study examines effects of cognitive impairment, age, gender
The random forest predictor of sex-associated differences in DNAm across the various odontocete species led to an OOB error of 0.5 percent, i.e., it misclassified two animals. We identified four CpGs that are highly differentially methylated across sex (Supplementary Fig.3). Three CpG probes ...
Participants were classified as having hypertension if the systolic blood pressure was ≥140 mm Hg or the diastolic blood pressure was ≥90 mm Hg at any clinic visit or exam antecedent to DNA collection, or if the participant was receiving treatment with an antihypertensive medication and had a...