We report here that selective Fc-afucosylation of PfEMP1-specific IgG1 increases with age in P. falciparum-exposed children and is associated with reduced risk of anemia, independent of the IgG levels. A similar association was found for children having PfEMP1-specific IgG1 inducing multiple ...
1c). We hypothesized that the average controllability of control hubs and large-scale networks would be negatively related to participants’ age. Next, we investigated how redundancy, a measure of multi-step paths between nodes, supports average controllability in middle- and old-aged participants ...
However, consider a child's age and maturity level. For example, if a child is extremely impulsive, it might be best to wait until he or she is older than 12. There appear to be very few states with specific regulations about the age of a child left at home alone. However, since th...
The succession of the gut microbiota during the first few years plays a vital role in human development. We elucidate the characteristics and alternations of the infant gut microbiota to better understand the correlation between infant health and microbi
("TissueCB - TissueBA4") in the testNhoods() function. Currently, no other fixed effects can be included in the same model when a contrast is investigated. Sex and age had a much smaller effect when tested alone and will not considerably affect tissue variance whereas it is possible that...
We show that cell tropism of SARS-CoV-2, and expression of ACE2 and TMPRSS2 in nasal epithelial cell subtypes, differ between age groups. While ciliated cells are viral replication centres across all age groups, a distinct goblet inflammatory subtype emerges in infected paediatric cultures and ...
In order to elucidate age-specific profiles of immune responses against RSV protection, antibody responses were examined by using blood samples in both acute and convalescent phases obtained from child patients and adult patients. In addition to the serum neutralization activity, antibody responses to ...
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Paroxysmal kinesigenic dyskinesia is an episodic movement disorder caused by dominant mutations in the proline-rich transmembrane protein PRRT2, with onset
Moreover, few studies have focussed on women alone, and the majority of studies predominantly featured Caucasian populations. The Singapore Preconception Study of Long-Term Maternal and Child Outcomes (S-PRESTO) longitudinal preconception cohort, a deeply-phenotyped, multi-ethnic cohort of Asian women...