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The time courses of plasma concentrations in two patients receiving UFT/LV combination therapy measured by the UPLC-MS/MS method developed in this study are shown in Fig. 3. The two patients underwent partial hepatectomy for CRLM before starting UFT/LV chemotherapy. One patient received UFT three...
which is different in each micro-trench, and the time-to-death of the two daughter cells. Images show a representative cell that has divided before drug addition; both of its daughter cells die (overlay of the in-focus phase-contrast and PI fluorescence images). (b) Distribution of the ti...
• Department of Pharmacy, Maine Medical Center, Portland, ME, USA • Maine Medical Center Research Institute, Scarborough, ME, USA • Tufts University School of Medicine, Boston, MA, USA Sergey V. Ryzhov • Maine Medical Center Research Institute, Scarborough, ME, USA ...
Genetic polymorphisms of tumor necrosis factor (TNF) -α and its surface receptors, TNFRSF1A and TNFRSF1B have been examined in terms of susceptibility to various cancers. In this study, genetic polymorphisms of TNFRSF1B gene were evaluated Japanese esophageal squamous cell carcinoma (ESCC) ...
kg b. w. was chosen in this study. As it is within the linear pharmacokinetic range at a level as close as possible to the range of proposed human exposure, yet high enough to measure both aglycone (i.e., active) and conjugated (i.e., inactive) forms of BPA in samples analyzed13....
(cholecalciferol diluted in medium-chain triglycerides: Oleovit D3drops, Fresenius) or placebo (carrier oil of medium-chain triglycerides) loading dose, labeled with the randomization number, which were created and bottled by the in-house hospital pharmacy, so as to blind both study subjects and ...