However from Week 15 post LMP a feasibly low and decreasing frequency of maternal serum samples from normal pregnancies still had an AFP value below 10 mcg/liter; this value also represented the upper limit for 98.5% of the nonpregnant population. Thus 10 mcg/liter was found to be a useful...
the complex becomes bound to the solid phase via interaction of biotin and Please note streptavidin. The measured AFP value of a patient’s sample can vary depending on ▪ The reaction mixture is aspirated into the measuring cell where the the testing procedure used. The laboratory finding must...
Increased MSAFP values are also seen in multiple pregnancies38 and in normal singleton pregnancies in which the gestational age has been underestimated. Low MSAFP values have been associated with molar pregnancy, missed abortion, pseudocyesis, overestimated gestational age, and Down Syndrome.39 In a ...
For example, a 35-year-old woman has a risk of a Down syndrome term pregnancy of about 1:380, the risk is 1:120 if the AFP level is 0.40 multiples of the normal median (MoM) and 1:1800 if it is 2.50 MoM. Software providing computer assisted test interpretation has been produced to...