However the number of blood stained AF samples was over-represented in instances with significantly increased maternal serum AFP levels after AMN: the proportion of bloody taps among the U subjects with no significant increase in AFP after AMN was 1/121 (.8%) whereas the same proportion mounted...
5A-B). Together, these results indicate that AFP exerts its growth-promoting effect on HCC cells by suppressing the Fas-mediated extrinsic apoptotic pathway. In mouse liver tumor samples, we observed that high levels of AFP were usually accompanied by downregulated Fas expression (Fig. 4c and ...
Elevated serum AFP levels subsequently reappear during pregnancy and in conjunction with several malignant diseases. Cancer Management Alpha-fetoprotein (AFP) was first described as a human tumor-associated protein in 1964 by Tatarinov.4 Since then it has been shown that elevation of serum AFP above...
may exhibit abnormally high levels of MSAFP. Increased MSAFP values are also seen in multiple pregnancies 38 and in normal singleton pregnancies in which the gestational age has been underestimated. Low MSAFP values have been associated with molar pregnancy, missed abortion, ...
Alpha-Fetoprotein (AFP) Levels in Maternal Serum in Relation to Transabdominal Amniocentesis in Early Pregnancy242 patients 150 from Uppsala (U) and 92 from elsewhere (E) underwent successful amniocentesis (AMN) before the 20th gestational week with recovery of amniotic fluid (AF) specimens of ...
Kjessler B, Johansson SGO, Lidbjork G, Sherman MS (1977) AFP levels in maternal serum in relation to pregnancy outcome in 7158 pregnant women prospectively investigated during their 14–20 week post last menstrual period. Acta Obstet Gynecol Scand Suppl 69: 25–44...
The serum levels of human alpha-fetoprotein, AFP, choriogona- dotropin, hCG, placental lactogen, hPL, and pregnancy-specific beta 1-glycoprotein, SP1, are of no clinical significance in colorectal carcinoma. Eur J Cancer Clin Oncol 1981;17:1047-52....
The significance of mid-trimester maternal serum AFP and hCG levels, in the prediction of adverse pregnancy outcome.doi:10.5281/zenodo.6010868Georgios AndroutsopoulosNkonkos PTsiberiotes KDekabalas G
I have studied the impact of maternal smoking on the levels of maternal serum alpha fetoprotein (AFP) and free beta human chorionic gonadotrophin (hCG) during the second trimester in a large series (30 727) of self-reported smokers and non-smokers whose pregnancy resulted in the birth o...
The percentage of Con A non-reactive AFP was significantly lower in the presence of open neural tube defects (< 3.9%, n = 13) compared with that in normal pregnancy (range 6.4–25.2%, n = 25). In this retrospective analysis, 2 pregnancies affected by open neural tube defect escaped ...