b. The degree to which particles or chemicals are likely to combine: Hemoglobin has a high affinity for oxygen. Also called avidity. [Middle English affinite, relationship by marriage, from Old French afinite, from Latin affīnitās, from affīnis, related by marriage; see affined.] Usage...
3-DPG stabilizesthe deoxy form of hemoglobin in preference to the oxy form, thereby lowering the oxygen affinity of the molecule. The γ-chain ofHbFlacks the β143histidineresidue, and the resultant decrease in binding of 2,3-DPG to HbF accounts for the increased oxygen affinity of fetal ...
The second electron affinity is defined as the energy required to add an electron to each mole of a gaseous monovalent anion to produce 1 mole of a bivalent anion (2-). This process is likely to happen in the group 16 elements oxygen and sulfur, which both form bivalent anions....
(at least one of them being an acetate) were energetically favored to bind aluminium in the whole range ofdielectric constants. In fact, these kind of multidentate ligands with negative oxygen donors are known to be the bestchelatorsfor Al(III) [24]. The main example is citrate, which, ...
If the value of electron affinity orEeais negative, it means energy is required to attach an electron. Negative values are seen for the nitrogen atom and also for most captures of second electrons. It can also be seen for surfaces, such asdiamond. For a negative value, the electron capture...
oxygen transportallosteric effectorsallosteryHemoglobinHemoglobin and myoglobin have been considered for a long time the paradigmatic model systems for protein function, to the point of being defined the "hydrogen atom[s] of biology" [Frauenfelder et al. Proc. Natl. Acad. Sci. USA, 2003; 100, ...
We show that PSGL-1 signalling is sufficient to induce E þ , whereas chemokine signalling necessary for H þ . Beyond these results that are relevant to our understanding of basic integrin biology, we discovered that E À H þ integrins bind ICAMs in cis, which effectively inhibits ...
The affinity of mammalian hemoglobin for oxygen is thought to be regulated primarily by 2,3-BPG levels and pH (the Bohr effect). However, our results show that increased endogenous levels of ATP and ADP, but not AMP, directly increase the p50 value of hemoglobin. Additionally, the rise in...
Electron affinity of the water dimer (in eV) with 6-31+G**, 6-311 + +G(3df,2p) and a basis set built by adding to the standard 6-31G set two sp and two d shells of diffuse functions on the oxygen centres and one s and two p on the hydrogen ones at different level of ...
3d). Importantly, the hydrogen bonds to the β6-α7 peptide backbone stabilize the orientation of the carbonyl oxygen of the residue in the −1 position, which coordinates to the ADMIDAS metal ion (Fig. 3c, d). The Ser residue in the +1 position of the (Asp/Asn)-Ser motif of ...