In subject area: Biochemistry, Genetics and Molecular Biology A membrane oxygenator must oxygenate per unit time a defined amount of blood having a given oxygen-binding capacity and venous saturation up to a desired level of arterial saturation. ...
b. The degree to which particles or chemicals are likely to combine: Hemoglobin has a high affinity for oxygen. Also called avidity. [Middle English affinite, relationship by marriage, from Old French afinite, from Latin affīnitās, from affīnis, related by marriage; see affined.] Usage...
oxygen transportallosteric effectorsallosteryHemoglobinHemoglobin and myoglobin have been considered for a long time the paradigmatic model systems for protein function, to the point of being defined the "hydrogen atom[s] of biology" [Frauenfelder et al. Proc. Natl. Acad. Sci. USA, 2003; 100, ...
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incorporate radioactive carbon (14C; half-life=5730 years), and/or radioactive hydrogen (3H; half-life of 12.3 years) to make the hormones radioactive for long intervals of time. Neither14C nor3H is hazardous to health. There is no radioactive form of oxygen for carboxyl and hydroxyl ...
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The affinity of mammalian hemoglobin for oxygen is thought to be regulated primarily by 2,3-BPG levels and pH (the Bohr effect). However, our results show that increased endogenous levels of ATP and ADP, but not AMP, directly increase the p50 value of hemoglobin. Additionally, the rise in...
3d). Importantly, the hydrogen bonds to the β6-α7 peptide backbone stabilize the orientation of the carbonyl oxygen of the residue in the −1 position, which coordinates to the ADMIDAS metal ion (Fig. 3c, d). The Ser residue in the +1 position of the (Asp/Asn)-Ser motif of ...
The affinity of mammalian hemoglobin for oxygen is thought to be regulated primarily by 2,3-BPG levels and pH (the Bohr effect). However, our results show that increased endogenous levels of ATP and ADP, but not AMP, directly increase the p50 value of hemoglobin. Additionally, the rise in...
If the value of electron affinity orEeais negative, it means energy is required to attach an electron. Negative values are seen for the nitrogen atom and also for most captures of second electrons. It can also be seen for surfaces, such asdiamond. For a negative value, the electron capture...