上海玉博生物科技有限公司做为tulip biolabs代理商之产品4301-Af1521 Macrodomain Affinity Resin Set (agarose beads)的产品销售公司,专业经营原装进口抗体(单克隆、多克隆)、重组蛋白、检测试剂盒、标准品、细胞因子、胎牛血清、细胞培养类等生物试剂以及耗材。
Af1521 macrodomainAffinity purificationETDEThcDMass spectrometryPARGPARPPTMProteomicsADP-ribosylation is a posttranslational modification (PTM) that has crucial functions in a wide range of cellular processes. Although mass spectrometry (MS) in recent years has emerged as a valuable tool for profiling ...
Random mutagenesis was used here to develop an engineered Af1521ADP-ribose binding macro domain protein with 1000-fold increased affinity towards ADP-ribose. The crystal structure reveals that two point mutations K35E and Y145R form a salt bridge within the ADP-ribose binding domain. This forces...
Here, we describe biochemical methods for detection of ADP-ribose conjugated to the androgen receptor (AR) using the archaeal macrodomain, AF1521, from Archaeoglobus fulgidus. The utility of AF1521 is based on its highly selective recognition of ADP-ribose conjugated to protein. AF1521 immobilized...
上海玉博生物科技有限公司做为tulip biolabs代理商之产品4301-Af1521 Macrodomain Affinity Resin Set (agarose beads)的产品销售公司,专业经营原装进口抗体(单克隆、多克隆)、重组蛋白、检测试剂盒、标准品、细胞因子、胎牛血清、细胞培养类等生物试剂以及耗材。 ATCC sigma anatrace caroteNature NIBSC medkoo thermo...