Ngai SH (1961) The effects of morphine and meperidine on the central respiratory mechanisms in the cat: The action of levallorphan in antagonizing these effects. J Pharmacol Exp Ther 131: 91–102 PubMedCASGoogle Scholar Freye E, Härtung E (1981) Fentanyl in the fourth cerebral ventricle c...
In Myocardial Infarction 48], and RE-LY [Randomized Evaluation of Long-Term Anticoagulation Therapy]) from the COMBINE-AF (A Collaboration Between Multiple Institutions to Better Investigate Non-Vitamin K Antagonist Oral Anticoagulant Use in Atrial Fibrillation) cohort were pooled; all patients with ...
(WATCHMAN Left Atrial Appendage System for Embolic Protection in Patients With Atrial Fibrillation; NCT00129545; and Evaluation of the WATCHMAN LAA Closure Device in Patients With Atrial Fibrillation Versus Long Term Warfarin Therapy; NCT01182441) Central Illustration Download: Download high-res image (...
Full size image MLL-AF4 enrichment at enhancers correlated with elevated H3K27ac and enhancer RNA (eRNA) transcription, suggesting that MLL-AF4 is associated with high levels of enhancer activity (Fig. 2c). Surprisingly, knockdown of MLL-AF4 (Supplementary Fig. 4c, d) resulted in a general...
Malignant neoplasms—Jasmiel is contraindicated in women who currently have or have had breast cancer because breast cancer may be hormonally sensitive. Liver disease—Discontinue COCs if jaundice develops. Hepatic adenomas and very rare hepatocellular carcinomas are associated with long-term (>8 years...
Author Contributions: Dr Reiffel had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis. Study concept and design: Reiffel, Verma, Kowey, Halperin, Ziegler. Acquisition, analysis, or interpretation of data:...
and a passion for people to transform the future of medical intervention and empower everyone to live their best life possible. For more than a century, we have driven breakthrough scientific innovation to address unmet needs and reimagine health. In surgery,...
Full size image To determine if heterogeneity in CD133 expression was observed in ALL patient samples, we analyzed 44 primary precursor B-ALL samples: 12 MLLr and 32 non-MLLr (sorting strategy shown in Supplementary Fig. 1e). Although there was a wide range of CD133 expression (measured by...
Full size table In the final multivariable model for the EAST-AFNET 4 defined primary outcome, heart failure was associated with a nonsignificant trend for increased risk (HR: 1.21, 95% CI 0.98–1.50, p = 0.075). For the occurrence of MACEs, paroxysmal AF was associated with an incre...
Effect of Catheter Ablation vs Antiarrhythmic Drugs on Mortality, Stroke, Bleeding, and Cardiac Arrest in AF JAMA Original Investigation April 2, 2019 This randomized trial compares the effect of pulmonary vein isolation via catheter ablation vs rate and rhythm control using medical therapy on a ...