The aetiology (or cause) of type 2 diabetes is broadly understood, although the details of the pathological processes remain obscure. There are four mechanisms that can be regarded as having an influence on the emergence of the disease: genes, beta-cell failure, insulin resistance and toxic ...
epidemiological studies on the role of environmental factors in the etiology of Type 2 diabetes mellitus is still scarce, there seems to be no doubt that lifestyle which predisposes to the development and increase of obesity explains part of the observed increasing rates of Type 2 diabetes world-...
Globally, about 1 in 11 adults have diabetes mellitus (90% have type 2 diabetes mellitus (T2DM)), and Asia is the epicentre of this global T2DM epidemic. The major driving factors of the global T2DM epidemic include overweight and obesity, sedentary lifestyle and increased consumption of unheal...
Chronotropic incompetence during exercise in type 2 diabetes: aetiology, assessment methodology, prognostic impact and therapy. Sports Med. 2015;45:985-95.Keytsman C, Dendale P, Hansen D. Chronotropic incompetence during exercise in type 2 diabetes: etiology, assessment methodology, prognostic impact...
New gene variants alter type 2 diabetes risk predominantly through reduced beta-cell function. PURPOSE OF REVIEW: Over the past 18 months, the number of gene loci robustly associated with type 2 diabetes has risen from three to 18. In this study, we ... JR Perry,TM Frayling - 《Curr Opi...
Dr. Jim Mann of the Radcliffe Infirmary Oxford concluded his recent chapter on the nutritional factors that cause diabetes type II (NIDDM) by stating that there was strong evidence that fibre-depleted starch foods are a risk factor.1 I had stated in 1975 that the prolonged consumption of ...
Metabolomics and type 2 diabetes risk: an updated systematic review and meta-analysis of prospective cohort studies. Diabetes Care 45, 1013–1024 (2022). Article CAS PubMed PubMed Central Google Scholar Wang, T. J. et al. Metabolite profiles and the risk of developing diabetes. Nat. Med....
Ketosis-prone diabetes (KPD) is a heterogeneous syndrome characterized by patients who present with diabetic ketoacidosis or unprovoked ketosis but do not necessarily have the typical phenotype of autoimmune type 1 diabetes. In this case report, we expose the difficulties in the diagnosis aetiology of...
Aims/hypothesis Epidemiological and experimental evidence suggests that uric acid has a role in the aetiology of type 2 diabetes. Using a Mendelian randomi... R Pfister,D Barnes,R Luben,... - 《Diabetologia》 被引量: 135发表: 2011年 The association of attention deficit hyperactivity disorder ...
In the longer term, treating the high prevalence of obesity, type II diabetes and cardiovascular illness in patients with schizophrenia has the potential to minimise the cognitive decline associated with these comorbidities. However, while there has recently been great progress in the detection and mon...