The World Health Organization (WHO) defines an adverse drug reaction (ADR) as “a drug-related event that is noxious and unintended and occurs at doses used in humans for prophylaxis, diagnosis or therapy of disease or for the modification of physiological function.” ...
Department of PharmacologyDwivediDepartment of PharmacologyShridharDepartment of PharmacologyIndian Journal of PharmacologyDeepti Chopra, Pooja Arnra, Shamimullah Khan, et al. Anaphylaxis following intravenous ranitidine: A rare adverse reaction of a common drug[J]. Indian J Pharmaeol, 2014, 46 (2): ...
cytochrome P450, while the interaction of ranitidine with this system is weaker. Consequently, cimetidine reduces the metabolism of many drugs which are normally degraded by phase I reactions, leading to potentially toxic plasma concentrations of therapeutic agents such as some oral anticoagulants, β-b...
Which of the following is a common adverse reaction of adrenergic drugs? a. Bradycardia b. Increase in appetite c. Decreased blood pressure d. Drowsiness 1. Where do the primary effects of adrenergic and b-adrenergic blocking drugs occur? 2. What adrenergic and b-adrenergic blocking drugs...
Identify as rapidly as possible the drug inducing the reaction and always opt for its withdrawal; in some circumstances the choice is difficult as there is no alternative drug and its use is essential for the maintenance of life; 1 A careful and intensive observation is recommended for the occu...
We present a patient who developed an anaphylactic reaction after one tablespoon of ranitidine. The goal of this manuscript is to add to the paucity of literature of this rare but life-threatening adverse effect of a commonly used medication....
The case is presented of a 36-year-old patient with Behçet's syndrome, who at the beginning exhibited signs of polymyositis and rheumatoid arthritis. About a year after the signs of Behçet's syndrome had started, a large leg ulcer appeared, which showed no healing tendencies. The patient...
5. Neutrophils and idiosyncratic adverse drug reactions resulting from inflammation-drug interaction: Ranitidine and diclofenac as examples [D] . Deng, Xiaomin. 2008 机译:炎症-药物相互作用引起的中性粒细胞和特异药物不良反应:雷尼替丁和双氯芬酸为例 6. Unexpected outcome (positive or negative) inc...
Ranitidine was found to have little effect on the pharmacokinet- ics of nifedipine, although there was an increase in the bioavail- ability of nifedipine during use of ranitidine.5 Famotidine has been reported not to interact with nifedipine.6 1. Kirch W, et al. Einfluß von cimetidin ...
“a response to a drug which is noxious and unintended and occurs at doses normally used in man for prophylaxis, diagnosis or therapy of disease, or for the modification of physiological function. This appreciably harmful or unpleasant reaction, predicts hazard from future administration and ...