The effects of testosterone on lipid metabolism and cardiovascular risk remain uncertain. In each situation the testosterone replacement brings specific benefits but the overall goals of therapy are to establish and maintain secondary sexual characteristics, sexual function, sense of well-being, and to ...
Clinical review 1: Adverse effects of testosterone therapy in adult men: A systematic review and meta-analysis The risks of testosterone therapy in men remain poorly understood.#The aim of this study was to conduct a systematic review and meta-analyses of testosterone trials to evaluate the adver...
Potential adverse effects of long-term testosterone therapy Baillière's Clinical Endocrinology and Metabolism Volume 12, Issue 3,October 1998, Pages 521-534 Purchase options CorporateFor R&D professionals working in corporate organizations. Academic and personalFor academic or personal use only. ...
Comment on: “Untreated hypogonadism and testosterone replacement therapy in hypogonadal men are associated with a decreased risk of subsequent prostate cancer: a population-based study” Ari P. Bernstein Jason Codrington Ranjith Ramasamy Comments & Opinion14 Jul 2024International Journal of Impotence Resea...
摘要: Hormonal treatment of hypogonadism in thalassaemia major (TM) is a complex issue due to the co-existence of other contributing factors such as severity of iron overload, associated chronic liver disease and other endocrine complications....
the effects of antiretroviral therapy on testosterone levels and fat-free mass [with To the Editor鈥擠ub茅 et al. [1] analyzed free testosterone levels and fat-free mass over time following antiretroviral therapy. The authors concluded that increases in both parameters were higher among patients ...
Interactions Therapy with danazol may inhibit the hepatic metabo- lism of a number of drugs including carbamazepine (see p.475), ciclosporin (see below), and possibly tac- rolimus (see p.1845). Danazol may also enhance the effects of warfarin (see Sex Hormones under Warfarin, p.1431). ...
The mechanisms are unknown; however, there are studies examining the protective effect of testosterone, a physiologic sex divergence observed at puberty. Despite both sexes having similar prepubertal baseline QTc, men experience a shortening of baseline QTc measurements.10,11,13 Women have been ...
Current male contraceptive methods under evaluation attempt to suppress sperm count to <1 million/mL and include a testosterone plus progestin topical gel. Are contraceptives associated with increased rates of cancer? Combined hormonal contraceptives, such as combined oral contraceptive pills, protect ...
discontinuation of multi-kinase inhibitor (MKIs), imatinib therapy due to TKI-associated adverse effects.10Toxicity can be attributed to bothon-targeteffects through excessive inhibition of the intended TK function; and/oroff-targeteffects resulting from the simultaneous inhibition of multiple other ...