Discusses an of the article, entitled `Diuretics and beta-blockers do not have adverse effects at 1 year on plasma lipid and lipoprotein profiles in men with hypertension,' by M.R. Lakshman, D.J. Reda, B.J. Materson and others, published in the 1999 journal `Archives of Internal ...
Effects of Hydrochlorothiazide on the Pharmacokinetics, Pharmacodynamics, and Tolerability of Canagliflozin, a Sodium Glucose Co-transporter 2 Inhibitor, i... The overall incidence of adverse events (AEs) was higher with canagliflozin + HCTZ (69%) than with canagliflozin (47%) or HCTZ (50%) alone...
Hydrochlorothiazide (HCTZ) is one of the most widely prescribed antihypertensive medications. Although it is well known that HCTZ is associated with hyperglycemia and hypertriglyceridemia, the mechanisms underlying these adverse effects are not well understood. We performed a genome-wide association study ...
Jounela AJ, Lilja M, Lumme J, et al: Relation between low dose of HCTZ, antihypertensive effect and adverse effects. Blood Press 1994; 3: 231-235.JOUNELA A J,LILJA M,LUMMEJ. Relation between low dose of hydrochlorothiazide,antihypertensive effect and adverse effects[J].BLOOD PRESSURE,...
These advantages of CTD over HCTZ are consistent with greater reductions in night-time blood pressure, greater reductions in oxidative stress and platelet aggregation, and greater improvements in endothelial function. CONCLUSION :Over the short-term there were no differences in the net clinical benefit...
These advantages of CTD over HCTZ are consistent with greater reductions in night-time blood pressure, greater reductions in oxidative stress and platelet aggregation, and greater improvements in endothelial function.CONCLUSION\nOver the short-term there were no differences in the net clinical benefit ...
This effect may be due to slightly better blood pressure reduction because addition of HCTZ enhances the cardio- and nephroprotective capacity of ENP. In contrast, OMA reduces TGF-尾 overexpression in the non-clipped kidney better than ENP or ENP + HCTZ. Therefore, vasopeptidase inhibition is ...
The purpose of this study was to assess the safety and antihypertensive dose-response effects of irbesartan and hydrochlorothiazide (HCTZ) in patients with mild-to-moderate hypertension. After a 4- to 5-week single-blind placebo lead-in period, 683 patients with seated diastolic blood pressure (...