More than 150 years after bromide was introduced as the first antiepileptic drug, adverse effects remain a leading cause of treatment failure and a major determinant of impaired health-related quality of life in people with epilepsy. Adverse effects can develop acutely or many years after starting ...
Adverse effects of antiepileptic drugs on bone mineral density in children. Expert Opinion on Drug Safety 2007 6 267-278. (doi:10.1517/14740338.6.3.267)... T Gissel,CS Poulsen,P Vestergaard - 《Expert Opinion on Drug Safety》 被引量: 69发表: 2007年 Review of pulmonary adverse effects of in...
Are adverse effects of antiepileptic drugs different in symptomatic partial and idiopathic generalized epilepsies? The Portuguese-Brazilian validation of the Liverpool Adverse Events Profile. Epilepsy Behav EB. 2011;22:511–7. https://doi.org/10.1016/j.yebeh.2011.08.005. Article CAS Google Scholar ...
The most prevalent of the CNS adverse effects observed during AED therapy are sedation, somnolence, distractibility, insomnia and dizziness. Sedation, in particular, is associated with most of the commonly used AED therapies. Nevertheless, cognitive function in individuals with epilepsy may also be ...
Strategies to detect adverse effects of antiepileptic drugs in clinical practice. Epilepsy Behav, 2008; 13: 178-183.Carreno M, Gil-Nagel A, Sanchez JC, et al. Strategies to detect adverse effects of antiepileptic drugs in clinical practice. Epilepsy Behav 2008; 13: 178-183....
The Korean version of the Liverpool Adverse Events Profile (K-LAEP) was applied to detect adverse effects of antiepileptic drugs (AEDs). Suicidality was ... S Jong-Geun,L Jang-Joon,CY Won,... - 《Journal of Clinical Neurology》 被引量: 84发表: 2015年 The Liverpool Adverse Events Profile...
Antiepileptic drugs (AEDs) are the mainstay of treatment. Chronic use, however, often leads to serial drug changes over time, exposing patients with epilepsy (PWE) to recurrent risks due to adverse effects (AEs) and drug interactions. Both unwanted acute and chronic AEs may occur that are ...
In determining the role of new antiepileptic drugs such as lamotrigine, vigabatrin, felbamate, and gabapentin a proper evaluation of both efficacy and adverse effects is required. 展开 关键词: BASAL GANGLIA FUNCTION STEREOTAXIC SURGERY DOI: 10.1017/S0317167100040749 被引量: 13 ...
Effects of Treatment on Endocrine Function in Patients with Epilepsy. Antiepileptic drug (AED) treatment is associated with multiple short- and long-term side effects. Effects on endocrine function, including weight change, r... A Pack - 《Current Treatment Options in Neurology》 被引量: 93发表...
Beneficial and Adverse Psychotropic Effects of Antiepileptic Drugs in Patients with Epilepsy: A Summary of Prevalence, Underlying Mechanisms and Data Limit... Topiramate, vigabatrin, levetiracetam, tiagabine and zonisamide have been associated primarily with adverse psychotropic effects, whilst gabapentin, pre...