Current applications of human pluripotent stem cells: possibilities and challenges Cell Transplant., 21 (2012), pp. 801-814 Google Scholar [20] S.S. Hung, S. Khan, C.Y. Lo, A.W. Hewitt, R.C. Wong Drug discovery using induced pluripotent stem cell models of neurodegenerative and ocular...
Advances and challenges in stem cell culture Stem cells (SCs) hold great promise for cell therapy, tissue engineering, and regenerative medicine as well as pharmaceutical and biotechnological applicat... McKee, Christina,GR Chaudhry - 《Colloids & Surfaces B Biointerfaces》 被引量: 7发表: 2017年 ...
Despite many reports of putative stem-cell-based treatments in genetic and degenerative disorders or severe injuries, the number of proven stem cell therapies has remained small. In this Review, we survey advances in stem cell research and describe the c
The article will also review the key advances in the development of biomaterial scaffolds and biomolecules aiming to control the cell response, as well as the possible challenges in this scientific field.doi:10.2174/2211542002666140107002020Cimpean Anisoara...
There is a further need to distinguish between the committed fate (defined during normal ) and the potential specification (implying flexibility of fate through manipulation of its environment) of stem cells undergoing differentiation. 6. With these challenges lying ahead, it is the opinion of the ...
Xeno-free derivation and culture of human embryonic stem cells: current status, problems and challenges. Human embryonic stem cells (hESC) not only hold great promise for the treatment of degenerative diseases but also provide a valuable tool for developmental... Ting,Lei,Sandrine,... - 《Cell...
Mesenchymal stem cells (MSCs) have emerged as the most extensively researched and applied stem cells in regenerative medicine [4]. Their therapeutic potential can be attributed to cell homing, promotion of cell differentiation, and secretion of bioactive factors [5, 6]. Actually, most of the ste...
Pluripotent stem cells in regenerative medicine: challenges and recent progress. After years of incremental progress, several recent studies have succeeded in deriving disease-relevant cell types from human pluripotent stem cell (hPSC) ... V Tabar,L Studer - 《Nature Reviews Genetics》 被引量: 322...
Insect Cell Culture: Recent Advances, Bioengineering Challenges and Implications in Protein Production The insect cell culture-baculovirus expression vector system has become popular for protein production. However, extensive information about the requiremen... LA Palomares,OT Ramirez 被引量: 11发表: 1998...
Finally, we will discuss the possible use of novel 3D in vitro culture systems to address many of the open questions in neuroblastoma biology. 2. Tumour microenvironment Tumours can be classified as organs based on their multi-tissue organisation and their continual response to different environments...