5 ' AMP-activated protein kinase (AMPK) is a master regulator of cell metabolism. It plays a significant role in the metabolism of PCa; hence, it can serve well as a treatment option for the advanced stages of PCa. However, whether this pathway contributes to cancer cell survival or death...
A new study led by investigators at the UCLA Health Jonsson Comprehensive Cancer Center found Black men diagnosed with more advanced stages of prostate cancer are significantly less likely to be prescribed novel hormone therapy than other racial and ethnic groups—including white or Latino men—despite...
There is a dramatic revolution under way in the treatment of advanced-stage prostate cancer, which for many years consisted of systemic chemotherapy that offered only palliation of symptoms and no hope of improved survival. The last decade has witnessed the debut of a completely new arsenal of ...
To estimate the total healthcare costs and costs attributable to prostate cancer across all stages of disease, and to determine the predictors of those cos... MD Krahn,B Zagorski,A Laporte,... - 《Bju International》 被引量: 120发表: 2010年 Enhancing Prostate Cancer Care Through the Multidis...
Screening of cancer is the maximum effort and critical element for providing health related care in order to decrease cancer related dealt because of the disease burden is in its advanced stages. Unfortunately, advanced-stage presentation and late diagnosis of cancers endure a problem in low-income...
Changes in prostate cancer(PC) screening protocols have led to an evolution in the type of disease that physicians are encountering when patients first enter the clinic, a panel of experts said during a recent OncLive Peer Exchange®.“We are seeing, especially in the urology office, patients...
Introduction The definition of advanced prostate cancer is confusing: T4, T3b and also T3a prostate cancer stages are considered by many as advanced diseases and the treatment advocated is often hormonal treatment in combination with radiotherapy. Furthermore, clinically node positive, pathologically nod...
and even halted for a period of time. Hormone therapy will eventually fail, however, and the prostate cancer will continue to grow and spread. This is calledhormone refractory prostate cancerand is commonly seen during the advanced stages of prostate cancer. The next step is usually chemotherapy...
There is still a need for the continuation of large prospective, randomized studies in all stages of this common illness, to define the role of the different therapeutic options at our disposal. The urological and urooncological worlds must be patient and not jump to too many early conclusions ...
Tumors of five groups of patients, with (1) nonpalpable primary breast cancer, (2) palpable operable primary breast cancer, (3) loco-regionally advanced primary breast cancer, (4) first and (5) late metastatic breast cancer, were studied in respect to their steroid receptor content. A statis...