OVARIAN cancerGYNECOLOGYOvarian cancer represents the fifth cause of cancer death among women, carrying one of the worst prognoses among gynaecological malignancies. The need to achieve no residual disease after surgery in order to optimize prognosis of advanced-stage ovarian cancer introduced...
Purpose The advent of multigene panels has increased genetic testing options for women with epithelial ovarian cancer (EOC). We designed a decision model to compare costs and probabilities of identifying a deleterious mutation or variant of uncertain significance (VUS) using different genetic testing ...
Nadir CA-125 serum levels during neoadjuvant chemotherapy and no residual tumor at interval debulking surgery predict prognosis in advanced stage ovarian cancer... K Nakamura,Y Kitahara,T Nishimura,... - 《World Journal of Surgical Oncology》 被引量: 0发表: 0年 Phase II Feasibility Study of Se...
Matthew Hadfield, DO, discusses his passion for early-stage clinical trials and the need for more research into immunotherapy toxicities during the third episode of Emerging Experts. Listen TORL-1-23 Well Tolerated in CLDN6+ Solid Tumors, Including Platinum-Resistant Ovarian Cancer ...
It constitutes about 0.5% of all ovarian malignancies. During a 12-year period (1978–1989), 22 patients were treated at the National Cancer Institute, Cairo, Egypt. According to the FIGO classification system, 4 patients were allocated to Stage I, 2 were Stage II, 13 were Stage III, and...
We previously reported that cyclin E (CCNE1) amplification is strongly associated with resistance to treatment in serous ovarian cancer by high-resolution oligonucleotide copy number analysis. Dysregulation of cell cycle control has been implicated as the key event in human oncogenesis, and aberrant ex...
Majority of ovarian cancer patients have advanced disease (stage III or IV) at diagnosis and the prognosis of these patients is poor in spite of aggressive surgery. Therefore chemotherapy has gained a fundamental role in the therapeutic approach of ovarian cancer. Platinum compounds in combination wi...
Ovarian cancer is one of the deadliest diseases that affects females worldwide. The high mortality of this cancer is due to its poor prognosis; therefore, most cases are diagnosed at the advanced stage with metastatic functions [1,2]. In spite of advances in treatment over the past decade, ...
the size of tumor obviously,decrease ascites and metastatic foci,which contributes to the safety and thoroughness of operation;even though neoadjuvant chemotherapy doesn't improve short term prognosis significantly,it is still an important therapeutic schedule for patients with advanced ovarian cancer. ...
Since locally advanced lung cancer treated by surgical therapy alone has poor prognosis, we studied multimodality treatment with induction chemotherapy to improve survival. We report 3 patients of stage III lung cancer which were completely resected in whom we obtained pathological CR (complete response...