Advanced liver fibrosis was defined as congestive hepatic fibrosis score 3 or 4. Results Only 4 patients (4%) had liver stiffness values < 10 kilopascal (kPa). Liver-stiffness measurements correlated weakly with peak oxygen uptake on exercise testing and Fontan pressure but not with M odel for...
<sec> Objective To investigate the risk factors for the development of advanced liver fibrosis by analyzing the clinical features of patients with in nonalcoholic fatty liver disease (NAFLD) and advanced liver fibrosis, and to establ
The AST/ALT ratio, BARD score, FIB-4 and NAFLD fibrosis scores had negative predictive values greater than 90% (93%, 95%, 95% and 92% respectively). Positive predictive values were modest. In order to exclude advanced fibrosis liver biopsy could potentially be avoided in 69% with AST/ALT...
compared to placebo on two primary endpoints: NASH resolution (including a reduction in the nonalcoholic fatty liver disease [NAFLD] activity score by ≥2 points) with no worsening of fibrosis, and an improvement in fibrosis by at least one stage with no worsening of the NAFL...
NAFLD fibrosis score (NFS) can be used in outpatient services to identify chronic vascular complications besides advanced liver fibrosis in type 2 diabetes Author links open overlay panelRosa Lombardi a, Lorena Airaghi a, Giovanni Targher b, Gaetano Serviddio c, Gabriele Maffi a, Alessandro ...
Advanced liver fibrosis was defined as the presence of fibrosis grades 3–4 in the histological evaluation. Furthermore, TE (FibroScan®) and ultrasonography measures were performed in the entire cohort. Steatosis was graded as follows: Absent (score 0), echotexture of the liver is normal;...
A noninvasive enhanced liver fibrosis (ELF) blood test identifies patients with nonalcoholicfatty liverdisease (NAFLD) who are at increased risk of advanced fibrosis, according to a new study. According to the study researchers, when combined with the fibrosis-4 (FIB-4) score the ELF test may...
Fibroscan-based score to predict significant liver fibrosis in morbidly obese patients with nonalcoholic fatty liver disease. Obes Surg. 2020;30:1249–57. Article Google Scholar Ooi GJ, Clouston A, Johari Y, et al. Evaluation of the histological variability of core and wedge biopsies in non...
Liver fibrosis is associated with lifestyle-related diseases, including diabetes. The identification of diabetic patients with severe liver fibrosis is imp
Reliable and available non-invasive methods for hepatic fibrosis assessment are important in chronic liver disease (CLD). Our aim was to compare stepwise algorithms combining standard ultrasound with serum markers and transient elastography (TE) for dete