Traditionally, there has been a high local recurrence rate in rectal cancer and 10–40% of patients require a permanent stoma. Both short-course preoperative radiotherapy (SCPRT) and long-course preoperative chemoradiation (CRT) are used to reduce the risk of local recurrence and enable a curative...
Despite recent advances in CRC, the number of patients with advanced CRC has been in- creasing, raising concerns of the impact of advanced- stage disease on survival and patient prognosis [3]. Treatment of patients with unresectable or metastatic CRC remains a challenge, and an unfavourable ...
BMC Cancer (2021) 21:947 https://doi.org/10.1186/s12885-021-08690-y RESEARCH ARTICLE Open Access Randomized phase II study of SOX+B-mab versus SOX+C-mab in patients with previously untreated recurrent advanced colorectal cancer with wild-type KRAS (MCSGO-1107 study) Yujiro Nishizawa1†, ...