Provide education, training, and continuing professional development to equip them with the necessary knowledge, skills, and competences to make the most of the benefits of personalized medicine for patients and health systems Promote cross-disciplinary interaction to ensure better understanding of available...
Janssen has an agreement with the Yale Open Data Access (YODA) project to serve as the independent review panel for the evaluation of requests for clinical study reports and participant-level data from investigators and physicians for scientific research that will advance medical knowledge and public...
biomedical sciences, and related disciplines. JAR seeks to publish high-quality papers that: 1) describe significant and novel findings; and 2) advanced knowledge in a diversity of scientific fields in the form of original articles, short communications, reviews, case reports, or letters to the ...
A. et al. COSMIC: exploring the world’s knowledge of somatic mutations in human cancer. Nucleic Acids Res 43, D805–D811 (2015). Article PubMed CAS Google Scholar Download references Acknowledgements We thank the patients, their families, and caregivers for their participation in the study;...
Discussion To our knowledge, this is the first randomized phase 3 trial demonstrating the clinical benefit of targeting the IDH1 variant for patients with advanced cholangiocarcinoma with IDH1 mutation or any other solid tumor with IDH1 mutation. Ivosidenib demonstrated a 63% reduction in the risk of...
To the best of our knowledge, this study was comprehensive analysis of the associations of concurrent mutations with response to the dual inhibition of angiogenesis and EGFR in the first time. Median PFS in this trial was 15.1 months, corroborating other studies of EGFR-TKIs combined with anti-...
MYB-NFIB fusion transcript in adenoid cystic carcinoma: Current state of knowledge and future directions 2022, Critical Reviews in Oncology/Hematology Citation Excerpt : The peptidomimetic inhibitor (MYBMIM) demonstrated a dose-dependent effect on cell viability of MYB-activated cells along with a limit...
This led to a greater economic cohesion and unity across European countries and users by means of efficient communication of medical records and knowledge facilitated by the establishment of standards in equipment, software and terminology. In addition, this will lead to an improvement in the quality...
28 A further disparate rate of non-Hispanic Black participation of 2% was reported by a different group of investigators.29 Regardless of recent trends, there are limited data on the enrollment of patients from racial and ethnic minority groups in phase 1 cancer trials, and to our ...
Kubo T, Shinkawa T, Kikuchi Y et al (2021) Fundamental and essential knowledge for pathologists engaged in the research and practice of immune checkpoint inhibitor-based cancer immunotherapy. Front Oncol 11:679095. https://doi.org/10.3389/fonc.2021.679095 Brahmer JR, Drake CG, Wollner I et al...