We investigated the brain atrophy distribution pattern and rate of regional atrophy change in Parkinson's disease (PD) in association with the cognitive status to identify the morphological characteristics of conversion to mild cognitive impairment (MCI) and dementia (PDD). T1-weighted longitudinal 3T...
The current means for establishing its diagnosis are 1) brain biopsy, which is associated with risk of brain hemorrhage... JL Rubenstein,J Karch,SA Josephson,... - 《Cancer Research》 被引量: 0发表: 2006年 Failure to thrive, hepatic dysfunction, hypotonia, and cerebellar atrophy A 2-year...
In addition, whether different co-morbid and genetic conditions are associated with BA and AD is still uncovered in the general community. We hypothesized that ABA will show a pattern of brain atrophy that is distinct and only partially overlapping to the one that has been described for AD. ...
White matter atrophy in cerebral amyloid angiopathy. Neurology. 2020;95(5):e554–62. Article CAS PubMed PubMed Central Google Scholar Wilcock DM, Vitek MP, Colton CA. Vascular amyloid alters astrocytic water and potassium channels in mouse models and humans with Alzheimer’s disease. ...
Other studies show that deficits or dysregulation in brain metabolism is linked with aging-related cognition decline and that decline could be reversed through nutrients and vitamin supplements such as acetyl-L-carnitine, vitamin B6, and vitamin B12 [139–151]. L-Tyrosine is a precursor to L-dop...
Methodological considerations for measuring rates of brain atrophy. PURPOSE: To systematically compare two techniques for measuring brain atrophy rates from serial magnetic resonance imaging (MRI) studies. MATERIALS AND MET... JL Gunter,MM Shiung,A Manduca,... - 《Journal of Magnetic Resonance ...
Also, older age has been demonstrated to strongly predict the level of fluid intelligence decline after damage to the frontal lobes, even more so than lesion location, level of brain atrophy or white matter abnormalities (Cipolotti et al., 2015). Thus, our results accord with findings that ...
Twelve cases of adult-onset progressive muscular atrophy variant of amyotrophic lateral sclerosis (PMA/ALS) were studied in a small rural population of 150... Larisa Cervenakova and Iosif I Protas and Asao Hirano and Veniamin I Votiakov and Mikhail K Nedzved and Natalia D Kolomiets and Inna...
microglia, the brain’s resident immune cells, are an attractive target for potentially more effective therapeutic strategies. However, there is no current in vitro model system that captures AD patient-specific microglial characteristics using physiologically relevant and experimentally flexible culture condi...
Greater regional brain atrophy rate in healthy elderly subjects with a history of cigarette smoking Alzheimers Dement, 8 (2012), pp. 513-519 View PDFView articleGoogle Scholar Durazzo et al., 2014 T.C. Durazzo, et al. Smoking and increased alzheimer’s disease risk: a review of potential ...