It provides information on structure bioinformatics at various levels, with individual chapters covering introductory to advanced aspects, from fundamental methods and guidelines on acquiring and analyzing genomics and proteomics sequences, the structures of protein, DNA and RNA, to the basics of physical...
出版社:Springer 出版年:2014-11-13 页数:383 定价:USD 209.00 装帧:Hardcover ISBN:9789401792448 豆瓣评分 目前无人评价 评价: 写笔记 写书评 加入购书单 分享到 推荐 我要写书评 Advance in Structural Bioinformatics的书评 ···(全部 0 条) 谁读这...
Another key method for hot spot identification is alanine scanning mutagenesis. Alanine scanning mutagenesis (CAS) is a method where functional assays are performed on proteins with specific amino acids mutated to alanine. The advancements in structural bioinformatics have led to the development of in ...
Bioinformatics, Advance Access published online, Nov. 2004.Yuan, X., and Bystroff, C. 2005. Non-sequential structure-based alignments reveal topology-... X Yuan,B Christopher - 《Bioinformatics》 被引量: 126发表: 2005年 Embryopathic effects of thalidomide and its hydrolysis products in rabbit...
Change of a small number of residues D o In this review we will focus on structural bioinformatics w Often X-ray structures are similar to the (TCR)pMHC complex of studies investigating conformational changes in the (TCR)pMHC n interest. If only one or very few amino acids need to be ...
Janusz Dutkowski and Jerzy Tiuryn - 《Bioinformatics》 被引量: 233发表: 2007年 ScienceDirect - Current Opinion in Structural Biology : Entropy in protein folding and in protein—protein interactions The increasing availability of large-scale protein-protein interaction (PPI) data has fueled the effor...
Enzyme research encompasses the purification, characterization, identification, and applications of enzymes. Enzyme technology has entered a modern era in which bioinformatics, genetic engineering, and high-throughput screening by miniaturization of inst
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Structural bioinformatics Advance Access publication October 28, 2011 STRIKE: evaluation of protein MSAs using a single 3D structure Motivation: Evaluating alternative multiple protein sequence alignments is an important unsolved problem in Biology. The most accurate way of doing this is to use structural...
Advances in quantitative biomarker development have accelerated new forms of data-driven insights for patients with cancer. However, most approaches are limited to a single mode of data, leaving integrated approaches across modalities relatively underdev