SELF-DETERMINATION IN ADOLESCENTS AND ADULTS WITH FRAGILE X SYNDROME: THE RELATIONSHIP BETWEEN SELF-REPORT, PARENT PERCEPTIONS, AND INDIVIDUAL CHARACTERISTICSSelf-determination is a characteristic that encompasses an individual's abilities and attitudes to act as one's own agent (Wehmeyer, 1992). ...
The goal of this study was to determine whether a phosphodiesterase-4D (PDE4D) allosteric inhibitor (BPN14770) would improve cognitive function and behavioral outcomes in patients with fragile X syndrome (FXS). This phase 2 trial was a 24-week randomized, placebo-controlled, two-way crossover ...
Conclusions Findings highlight the elevated and ongoing use of medication by individuals with FXS. Implications for social and behavioural research on FXS are discussed. 展开 关键词: adolescents and adults fragile X syndrome non‐psychotropic medication psychotropic medication ...
Fragile X syndrome (FXS) is the most common monogenic cause of inherited intellectual and developmental disabilities. Mavoglurant, a selective metabotropic glutamate receptor subtype-5 antagonist, has shown positive neuronal and behavioral effects in preclinical studies, but failed to demonstrate any ...
DaWalt, L. S., Usher, L. V., Greenberg, J. S., & Mailick, M. R. (2017). Friendships and social participation as markers of quality of life of adolescents and adults with fragile X syndrome and autism.Autism, 23, 383.https://doi.org/10.1177/1362361317709202. ...
The Influence of Hyperactivity, Impulsivity, and Attention Problems on Social Functioning in Adolescents and Young Adults With Fragile X Syndrome. J Attention Disorde. 2015;23(2):181-8. https://doi.org/10.1177/1087054715571739. Sacchetti GM, Lefler EK. ADHD symptomology and social functioning in ...
In this study, the authors examined the expressive language abilities of a subset of highly verbally expressive adolescents and young adults with Down syndrome (DS) and those with fragile X syndrome (FXS) for evidence of syndrome-related differences. FXS gender differences were also examined in an...
Malan syndrome (MALNS), previously referred to as “Sotos syndrome 2” due to its resemblance to Sotos syndrome (SS), is an ultra-rare neurodevelopmental disorder characterized by overgrowth, typical craniofacial features, intellectual disability (ID), a
A comparison of language characteristics of mentally retarded adults with fragile X syndrome and those with nonspecific mental retardation and autism Fragile X syndrome is a recently identified form of mental retardation that is associated with a chromosomal abnormality and inherited in an X-linked manne...
valvar Mendelian syndrome Alagille syndrome268 Pulmonic stenosis, valvar Branch pulmonary stenosis tetralogy of Fallot ASD, VSD Cardio-facio-cutaneous (CFC) syndrome269,270 Pulmonic stenosis, valvar HCM Costello syndrome271,272 Pulmonic stenosis, valvar HCM Fragile X syndrome273 Mitral valve prolapse ...