Older adults aren't the only group impacted by RSV. Very young children have been at the center of this winter's unusually severe RSV surge, which is now seeingcasesclimbing down from a steep peak. Pfizer also has amaternal vaccinein the race, which would be given to parents-to-be in ...
lockdowns, quarantines), patients refraining from seeking health care services due to fear of being exposed to the virus, and providers withholding routine care to focus on addressing the pandemic all played a role in decreased vaccination rates.10...
It typically doesn't take long at all for you to start feeling sick after being exposed to a cold virus. "The most common colds have an incubation period—the time after exposure and before symptoms develop—from one to three days," says Dr. Zack. ...
For poly (I:C) stimulation, nasopharyngeal cells obtained from 8 children and 8 adults were exposed to poly (I:C) (25 μg/ml, Sigma-Aldrich, MO, USA; catalog no. P1530) for 4 h. Total RNA was isolated using Trizol reagent according to the manufacturer's instructions (Invitrogen, CA...
RSV and influenza virus, similarly to CMV, have a longer period of viral shedding if they are acquired earlier in life. Animal data support these findings: mice infected with lymphocytic choriomeningitis virus (LCMV) in utero or during the first 2 days of life develop a persistent ...
Older adults, as the population considered at increased risk for severe COVID-19, were the most impacted by social isolation. Thus, this study aimed to assess the salivary immune/inflammatory response of older adults before and during the COVID-19 pandem
RESULTS. The exposed population included 1152 participants aged 50–59 years and 381 participants aged ≥60 years. RSVPreF3 OA was immunologically noninferior in 50–59-year-olds versus ≥60-year-olds; noninferiority criteria were met for RSV-A and RSV-B neutralization titers in those with ...
To determine if these subpopulations of naïve T cells were unique to COVID-19 or were also present in individuals who had not been exposed to SARS-CoV-2, we examined the distribution of T cells in age-matched PBMCs from the OneK1K cohort [46] which was collected pre-2019 (Fig. 2E...
PCR methods are known to detect pathogens even just a few days after being exposed to antibiotics, which is difficult to detect with conventional bacterial culture [15]. We believe that molecular techniques are more appropriate for pathogen surveys because the results are less affected by pre-...
Safety/reactogenicity up to 1 month post-dose 1 are reported here.Exposed set was comprised of 48 YA and 1005 OA. Within 7 days post-dose 1, any solicited/unsolicited adverse event (AE) ranged from 58.3% to 83.3% across YA vaccinees (placebo YA: 58.3%) and from 29.9% to 84.2% ...