成人斯蒂尔病(Adult onset still’s disease,AOSD)是一组病因及发病机制不明的系统性炎症性疾病,以弛张热(≧39℃);易逝性充血性红色或桃红色斑丘疹;关节炎或关节痛;白细胞计数≧10,000/mm3(中性粒细胞≧80%)为主要特征。其命名可追溯到一个世纪前,1897年英国医生Georger Still报道在22例儿童RA中有12例为全身...
Adult-onset Still's disease (AOSD) is a rare systemic inflammatory disorder characterised by high spiking fever, an evanescent salmon pink rash and arthritis, frequently accompanied by sore throat, myalgias, lymphadenopathies, splenomegaly and neutrophilic leukocytosis. Aetiology is still unknown, ...
Adult-onset Still’s disease (AoSD was first described in the early 1970s, by Bywaters, as an inflammatory condition occurring in young adults. The disease was very similar to childhood-onset Still’s disease, today called systemic-onset juvenile idiopathic arthritis (SoJIA), described a century...
成人Still病(adult onsetstill disease,AOSD,变应性亚败血症),是以长期间歇性发热、一过性多形性皮疹、关节炎或关节痛、咽痛为主要临床表现,并伴有周围血白细胞总数及粒细胞增高和肝功能受损等系统受累的临床综合征。自Wissler(1943)首先报告后,Fancon(1946)相继描述,因其临床酷似败血症或感染引起的变态反应,故称之...
Adult-onset Still's disease (AOSD) is a systemic inflammatory disorder of unknown etiology and pathogenesis. Since a high fever is often the only manifestation, AOSD is regarded as an important cause of fever of unknown origin (FUO). The most important serological markers are hyperferritinemia,...
Adult-onset Still disease; neutrophil activation; pro-inflammatory cascade; anti-cytokine therapy 1. Introduction Adult-onset Still’s disease (AOSD) is a rare inflammatory disease with an unknown cause [1]. Bywaters, a London doctor, first used the term AOSD in the medical literature in 1971...
AdultStill’sDisease 定 义 是病因未明的以高峰热、一过性多形性皮疹、关节痛或关节炎、肝、脾、淋巴结肿大为主要临床表现,并有白细胞增多,RF及ANA阴性的一种临床综合征。名称演变 1897年GeorgeStill Still’sdisease (幼年类风湿关节炎全身型) 40年代Wissler-Fanconi综合征 1943年Wissler,1946年Fanconi...
Adult-onset still's disease:a report of 28 cases and review of the literature[J].{H}MODERN RHEUMATOLOGY,2008.480-485.Mehrpoor G, Owlia MB, Soleimani H et al (2008) Adult onset Still's disease: a report of 28 cases and review of the literature. Mod Rheumatol 18:480-485...
Collapsing glomerulopathy is a rare but important complication of Adult Still's disease. Immunosuppressive treatment may be effective in improving renal outcome.Nephrology Dialysis TransplantationArulkumaran, NishkanthaReitbock, PabloHalliday, KirstyOnwubalili, JamesJayasena, DakshinaDupont, Pe...
doi:10.1080/00325481.1975.11714179I J StrumpfJ D LazarJ T CassidyAmerican Family Physician