While there is a consensus among studies for a neuro- protective role of CX3CL1 signaling in vitro, some in vivo studies even suggest a neurotoxic role of CX3CL1 as seen in animal models for Alzheimer's- and Parkin- son's disease. Here, CX3CL1 can act as a repressor of microglial...
Comparisons showed similar protective effects of the mupirocin-CHG regimen for all 3 outcomes after more than 7 years of continuous universal ICU decolonization (Figure 3; eFigure 2 and eTable 5 in Supplement 2). For the hazard of S aureus clinical cultures by ICU-attributable day 30, ...
They demonstrate that many of the putative protective mechanisms by which hypothermia may act, especially apoptosis and inflammation, peak days after ischemia and reperfusion. Other mechanisms like neuro-, angio-, and gliogenesis only arise after several days and could only be potentially modified ...
Western blotting Tissue samples from the hippocampus and prefrontal cortex of offspring were homogenized in extraction buffer (C500006, Sangon Biotech, Shanghai, China) according to the manufacturer’s instructions. Each sample was adjusted to a final protein concentration of 1 μg/μl, mixed with ...
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