A major challenge to human health is that the adult human heart does not regenerate. Myocardial infarction (MI) causes a permanent non-contractile and non-conductive scar, which leads to chronic heart failure and arrhythmia. Much interest has followed the epicardium recently for its key role in ...
Owing to the prevalence and high mortality rates of cardiac diseases, a more detailed characterization of the human heart is necessary; however, this has been largely impeded by the cellular diversity of cardiac tissue and limited access to samples. Here, we show transcriptome profiling of 21,422...
Validation of a polar (R) human heart rate monitor for measuring heart rate and heart rate variability in adult dogs under stationary conditions. J Vet Behav. 2012;7(4):205-12.V. S. M. Jonckheer-Sheehy, C. M. Vinke, and A. Ortolani, "Validation of a polar human heart rate monitor...
Recent breakthroughs in the generation of pluripotent iPSCs via 'forced’ expression of specific genes (Oct3/4, Sox2, Klf4, c-Myc or Oct3/4, Sox2, Nanog, Lin28) in somatic cells [64, 65] might overcome some of the limitations of human ESCs for heart regeneration. As iPSCs are generat...
Recent breakthroughs in the generation of pluripotent iPSCs via 'forced’ expression of specific genes (Oct3/4, Sox2, Klf4, c-Myc or Oct3/4, Sox2, Nanog, Lin28) in somatic cells [64, 65] might overcome some of the limitations of human ESCs for heart regeneration. As iPSCs are generat...
Beta human chorionic gonadotropin (HCG): Female, premenopausal nonpregnant: ˂1.0 U/L; female, postmenopausal: ˂7.0 U/L; male: ˂1.4 U/L CA19.9: 0–37 U/mL Carcinoembryonic antigen (CEA): ˂2.5 ng/mL Prostatic acid phosphatase (PAP): 0-3 U/dL Prostate-specific antigen (...
Quantitative growth and development of human brain No abstract available. J Dobbing,J Sands - 《Archives of Disease in Childhood》 被引量: 2502发表: 1973年 Effect of Very Low Birth Weight and Subnormal Head Size on Cognitive Abilities at School Age We tested the hypothesis that very-low-...
Rationale The capacity for cardiomyocyte regeneration in the healthy adult human heart is fundamentally relevant for both myocardial homeostasis and cardiomyopathy therapeutics. However, estimates of cardiomyocyte turnover rates conflict greatly, with a study employing C14 pulse-chase methodology concluding 1%...
partially through its interaction with integrins94. Laminin is commonly used as a precoating substrate to assist in the attachment of neurons and can increase the survival and growth of human pluripotent stem cell-derived neurons95. The addition of an extra layer of laminin coating on top of the...
PBNs isolated from asthmatic patients and HCs were untreated or treated with 100 ng/mL LPS for 2 h for ELISA. In some experiments, PBNs were primed with anti-S100A9 antibodies for 30 min and treated with 100 ng/mL recombinant human S100A9 or LPS for the indicated time (for wes...