For those who haven’t yet read this superlative modern love story, we’ll lay it out for you. Simon Spier is a regular teenager living in the Atlanta suburbs, with a solid group of friends, a pile of AP classes, and a happy (if slightly chaotic) family. But he hasn’t told anyone...
In tumour-progressing cells, EP2 receptor is highly expressed, while the EP3 receptor expression level is relatively ulolwat1e2,c13e.lTl phrisolCifOerXat-i2o/nPGanEd2 axis forms an autocrine/paracrine loop, affecting the cell cycle and apoptosis to viability via the activation of one or more ...
This finding is in line with observations that the most common co-occurring classes of mutations in MPNs are signaling mutations (e.g., JAK2V617F) and mutations in genes involved in epigenetic regulation (e.g., TET2) [75]. Progression in PV patients may result from co-occurring mutations ...