Primary adrenal insufficiency (Addison's disease) is a rare endocrine disease in which there is destruction of the adrenal cortex with resultant inadequate secretion of the adrenal cortical hormones – cortisol, aldosterone and androgens. From: Tuberculosis, 2009 ...
1、Adrenal Insufficiency (Addison's Disease): Treatment: Hormone replacement therapy is the mainstay of treatment. Patients with adrenal insufficiency require lifelong supplementation with glucocorticoids (e.g., hydrocortisone, 氢化可的松 prednisone泼尼松) to replace the deficient cortisol and sometimes min...
Background Primary adrenal insufficiency (PAI) is life-threatening, and a definitive aetiological diagnosis is essential for management and prognostication. We conducted this study to investigate the genetic aetiologies of PAI in South China and explore their clinical features. Methods Seventy children ...
Adrenal insufficiency should be the first consideration, especially with bilateral adrenal incidentalomas (AIs). A corticotropin test with 60-minute cortisol levels helps rule out the diagnosis. If found, suspect granulomatous disease, hemorrhage, or lymphoma. A 21-hydroxylase deficiency can also be dia...
Adrenal insufficiency has been documented in three individuals with mutations in the SF-1 gene. Two patients exhibited XY sex reversal due to the lack of gonads.3 Over 50 different mutations in the DAX-1 gene are associated with variable onset X-linked adrenal failure. Patients with DAX-1 ...
Medical tests for adrenal insufficiency start with blood cortisol levels, and tests for the ACTH hormone that stimulates the pituitary gland. "If the person does not have adrenal insufficiency and they're still fatigued, it's important to get to the bottom of it," Vouyiouklis Kellis says. ...
Although adrenal gland involvement is common among patients with advanced AIDS, the prevalence of clinical adrenal insufficiency in the pre-HAART era was reported to be 5–10%.25–27 Most commonly this was primary adrenal insufficiency, but some patients with secondary adrenal insufficiency were repor...
Molecular Basis of Adrenal Insufficiency KENJI FUJIEDA AND TOSHIHIRO TAJIMA Department of Pediatrics [K.J.], Asahikawa Medical College, Asahikawa 078-8510, Japan, Department of Pediatrics [T.T.], Hokkaido University School of Medicine, Sapporo 060-0835, Japan ABSTRACT Defective production of adrenal...
Google Share on Facebook adrenal (redirected fromadrenal-cortical) Thesaurus Medical Encyclopedia Related to adrenal-cortical:adrenal cortical insufficiency,adrenal cortical hyperplasia ad·re·nal (ə-drē′nəl) adj. 1.At, near, or on the kidneys. ...
Adrenal insufficiency.Adrenal insufficiency is a condition in which your adrenal glands don’t make enough cortisol. Primary adrenal insufficiency, also called Addison’s disease, occurs when something like an autoimmune disorder, cancer, or infection damages the adrenal gland. ...