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FIELD: medicine, pharmaceutics.;SUBSTANCE: what is presented is an agent for poly(ADP-riboso)polymerase inhibition. The agent represents 7-methylguanine(2-amino-7-methyl-1H-purin-6(7H)-one)- a purine derivative of formula (I) The agent has shown the efficacy higher than that in 7-methyl-...
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1. A method for modulating glucose homeostasis in a diabetic patient in need thereof comprising: contacting an islet cell with an effective amount of a first agent that increases intracellular levels of O-acetyl-ADP-ribose, said increase in concentration resulting in cellular depolarization and/or ...
重新启动,按住F8,进入安全模式,再从安全模式中启动杀毒软件就可以轻松杀毒 了。另外请问您计算机中病毒的位置是不是在:C:\Documents and Settings\用户名\Local Settings\Temporary Internet Files\ 如果是,请照以下方法操作即可删除病毒文件,1、右击Internet Explorer,选择"属性";2、在"常规"选项卡...
of (8S,9R)-5-Fluoro-8-(4-fluorophenyl)-9-(1-methyl-1H-1,2,4-triazol-5-yl)-2,7,8,9-tetrahydro-3H-pyrido[4,3,2-de]phthalazin-3-one (BMN 673, Talazoparib), a Novel, Highly Potent, and Orally Efficacious Poly(ADP-ribose) Polymerase-1/2 Inhibitor, as an Anticancer Agent 来自...
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Design and synthesis of 4″,6″-unsaturated cyclic ADP-carbocyclic-ribose, a Ca2+-mobilizing agent selectively active in T cellsADENOSINE 5'-DIPHOSPHATE RIBOSECONDENSATION REACTIONAPLYSIA-CALIFORNICACHEMICAL-SYNTHESISNORTHERN RIBOSECALCIUM-RELEASEANALOGS...
@Agent_Xenos @蒋小贤jyz10 @BIG肖恩_Upon_Tyne 【转发】@DelPiero:Ciao! Just to inform you that the Chinese edition of my book “GIOCHIAMO ANCORA” now is available. #ADP10# 嗨~我的中文自传已经公开发售...