Cell, Volume 175, Issue 5, 15 November 2018, Pages 1182-1184 Elizabeth A. Mueller, Petra Anne LevinView PDFHighlights Summary ADP-ribosylation of proteins can profoundly impact their function and serves as an effective mechanism by which bacterial toxins impair eukaryotic cell processes. Here, we...
(ADP-ribose) glycohydrolase (PARG) and (ADP-ribosyl)hydrolases (ARHs); the terminal ADP-ribose, or MAR, can be hydrolyzed by specific macrodomain proteins, such as MacroD1, MacroD2, and the terminal ADP-ribose protein glycohydrolase (TARG1) in mammals (Cohen and Chang, 2018; Rack et ...
The MePHD1-GFP protein was located in the nucleus of the onion epidermal cell, whereas the control GFP was dispersed in the entire cell (Figure 4). The result precisely demonstrated that MePHD1 was a nucleus-localized protein. Int. J. Mol. Sci. 2018, 19, 2831 5 of 11 wInti.tJh. ...
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The reaction was proposed to proceed in an SN1-like mechanism (Cohen and Chang, 2018; Han et al., 2001). The AcrIF11 residues involved in the catalytic reaction are marked in red. See also Figures S3, S5, and S7 and Tables S1, S2, and S3. ADP-Ribosylation of N250 of Cas8f ...