Naloxone is used intravenously in opiate addiction in emergency cases, in rapid opiate detoxification, and as a diagnostic tool. This is a study comparing the efficacy of intranasal naloxone to other routes (intravenous/intramuscular) in 17 opiate-dependent patients. The nasal drug administration of ...
Drugs that can be administered by the nasal route include naloxone (for reversing opioid overdose), nicotine (for smoking cessation), calcitonin (for osteoporosis), sumatriptan (for migraines), and corticosteroids (for allergies). Some drugs given by the nasal route have direct effects on the ...
Recent studies have demonstrated that intranasal (IN) naloxone is a safe and effective alternative to traditional routes of naloxone administration for reversal of opi... C Mcdermott,NC Collins - 《Emerg Med Int》 被引量: 29发表: 2012年 Impact of a pharmacist-prepared interim residential care ...
Laboratory animals will self-administer several classes of addictive drugs by the oral, intragastric, intraperitoneal, intravenous, or even intracranial routes and will do so in the absence of physical dependence (Bozarth and Wise, 1984; Gardner, 1997, 2000). In the strongest version of the mo...
largely bypasses hepatic first-pass metabolism and permits rapid and predictable bioavailability compared with oral medications and someintramuscular medications.4We review the literature and indications for out-of-hospital andEDadministration of intranasal midazolam,fentanyl,naloxone,ketamine, anddexmedetomidine....
The naloxone option: This quick guide provides you with naloxone dosing information and steps you'll want to take once the crisis has passed Thus, the main purpose of current work is to develop a thermosensitive gel formulation for intranasal administration of curcumin and therefore to obtain a ...
naloxone(for reversing opioid overdose),nicotine(for smoking cessation),calcitonin(for osteoporosis),sumatriptan(for migraines), and corticosteroids (for allergies). Some drugs given by the nasal route have direct effects on the lining of the nose such as nasal decongestants and corticosteroids (for ...
Acute systemic and intracranial nicotine pretreatment limits the acquisition of conditioned place preference (CPP) to lower doses of morphine and cocaine11,29,30 and conditioned place avoidance from naloxone-precipitated morphine withdrawal31,32. Additionally, across multiple commonly abused substances, ...
Open-label exploration of an intravenous nal- buphine and naloxone mixture as an analgesic agent following gynecologic surgery. Pain Med 2007; 8: 525–30. Preparations Proprietary Preparations (details are given in Part 3) Arg.: Gobbinal; Naltrox; Nubaina; Nubak†; Onfor; Austria: Nubain...
Nasal delivery has undeniably earned less attention among unconventional drug administration routes relative to other routes such as transdermal and pulmonary ones. Nasal drug administration has generally been concerned for treating mild clinical illnesses, such as nasal infections, rhinorrhea, nasal congesti...