As a result, several participants in the study did not realize that the survey included rollover definitions. Their mental models were correct in that moving the mouse over the term would produce a definition. However the delayed feedback provided by the survey changed theirinterpretation. By the...
26,27 The clinical community has generally accepted 30% to 50% of the difference between treatment and control conditions as an acceptable definition for the noninferiority margin,27,28 and noninferiority trials of pharmacologic treatments have used the 50% criterion.29-31 A recent meta-analysis ...
Participants with mild condition (see definition in Statistical analysis section) in leritrelvir group only had 1/43 patients (2.33%) presenting pneumonia imaging progression compared to 5/57 patients in placebo (8.77%). Patients with moderate condition in leritrelvir group had shorter median time...
Therefore, 50 mg m À 2 met the pre-specified RP2D definition, with 4 of 15 patients (o33%) experiencing DLT. In part 2, patients received an 8- or 24-h i.v. infusion of dinaciclib starting at the part 1 RP2D of 50 mg m À 2. There were two DLTs in two patients ...
Naturally occurring human IL-6 variants are known and included in this definition. Human IL-6 amino acid sequence information has been disclosed, see for example, www.uniprot.org/uniprot/P05231.For the purposes herein “human interleukin 6 receptor” (abbreviated as “IL-6R”) refers to the ...
Postpartum anemia I: definition, prevalence, causes, and consequences. Ann Hematol. 2011;90:1247–53. 16. Smith JM, Baawo SD, Subah M, Sirtor-Gbassie V, Howe CJ, Ishola G, et al. Advance distribution of misoprostol for prevention of postpartum hemorrhage (PPH) at home...
syndrome diagnosis were included); overall ratio of diagnoses corresponded to the ratio in the TCD-haplo group. Information was collected in a study-specific case report form for the selected patients. Patient and donor information collected is listed in the Supplementary information. Definition of en...
The definition of an investment dispute under Article VI (I) of the Treaty, the Claimant further asserts, is related to rights the investor has under the Treaty and has no connection with its claims pending in the courts of Ecuador, which involve exclusively the . consistency of the Denying ...
Definition of seroprotection Although WHO recommends 0.35 μg/mL as minimum protective concentration of anticapsular serotype-specific IgG antibodies [17], thresholds differ by serotype [3,18], and higher ones have been adopted for adults [19,20]. OPA antibody responses are generally accepted as ...
By definition, the equilibrium solubility of a compound refers to the most stable crystalline form. No ‘true’ solubility can be defined for higher energy solid forms (e.g., high-energy polymorphs or amorphous forms), since those can only exist in a metastable (and not thermodynamic) equilibr...