MF59-ADJUVANTED QUADRIVALENT INFLUENZA VACCINE PROVIDES CONSISTENT BENEFIT UPON REVACCINATION IN YOUNG CHILDRENIgor Smolenov
strain mismatch More susceptible to influenza2,3 Less able to generate a sufficient immune response to standard flu vaccines2,3 Can decrease vaccine effectiveness especially in an already vulnerable population4,5 7 out of 10 recent US flu seasons were impacted by strain mismatch*5-15 ...
Immunogenicity and safety of zoster vaccine live administered with quadrivalent influenza virus vaccine. Vaccine. 2018;36(1):179–85. Article CAS PubMed Google Scholar Schwarz TF, Aggarwal N, Moeckesch B, Schenkenberger I, Claeys C, Douha M, Godeaux O, Grupping K, Heineman TC, Fauqued ...
we used the current Dutch influenza tariff of €11.36 per dose, assuming that HZ vaccination would be provided in a GP-based programme [41]. This tariff covers, next to vaccine administration
Compared to the traditional quadrivalent split-virion influenza vaccine, a novel quadrivalent subunit influenza vaccine is urgently needed in China. We completed a phase 3, randomized, double-blind, active-controlled, non-inferiority clinical study at two sites in Henan Province, China. Eligible ...
Based on previous experience, an AS03-adjuvanted influenza candidate vaccine with 3.75 μg or 1.9 μg hemagglutinin (HA) was developed against the novel swine-origin H1N1/2009 pandemic influenza strain, which elicited immune responses that met US and European regulatory immunogenicity criteria in ...
Influenza vaccination is an important public health measure that can reduce disease burden, especially among older persons (those aged 65 and over) who have weaker immune systems. Evidence suggests enhanced vaccines, including adjuvanted quadrivalent vaccines (aQIV), may be part...
MF59-ADJUVANTED QUADRIVALENT SUBUNIT INFLUENZA VACCINE IS NON-INFERIOR TO THE LICENSED MF59-ADJUVANTED TRIVALENT VACCINE AND WELL-TOLERATED IN OLDER ADULTSIgor Smolenov
This study aimed to show the clinical efficacy of an MF59-adjuvanted quadrivalent influenza vaccine (aQIV) in adults 65 years or older compared with adults not vaccinated to prevent influenza. METHODS :We did a randomised, stratified, observer-blind, controlled, multicentre, phase 3 study at 89...
Quadrivalent adjuvanted haemagglutinin nanoparticle influenza vaccine: a step towards better protection of older adults from the constantly mutating H3N2 influenza virusesdoi:10.1016/S1473-3099(21)00209-7Irina Isakova-SivakDepartment of Virology, Institute of Experimental Medicine, Saint Petersburg, 197376 ...