The potential and limitations of a cell-seeded collagen/hyaluronan scaffold to engineer an intervertebral disc-like matrix. STUDY DESIGN: The use of a cell-seeded biomatrix for tissue engineering of the intervertebral disc. OBJECTIVE: To evaluate the ability of a biomatrix to su... M Alini,W...
While activation of NMDA receptors and increases in Ca++ in the post-synaptic density are key components of this process [4], additional factors contribute. One of these factors is the presence of peri-synaptic extracellular matrix (ECM), a lattice of chondroitin sulfate (CS)-bearing ...