The original concept of adipose tissue as an inert storage depot for the excess of energy has evolved over the last years and it is now considered as one of the most important organs regulating body homeostasis. This conceptual change has been supported by the demonstration that adipose tissue ...
White adipose tissue is a highly plastic organ and is an important regulator of whole-body metabolism and energy balance. The magnitude of adipose tissue m
1.1 Types of adipose tissue Adipose tissue functions in the storage of energy reserves, regulation of appetite, control of thermogenesis, and insulin sensitivity by secreting hormones (adipokines), cytokines, and lipids. The major form of adipose tissue is termed white adipose tissue (WAT) and exis...
Gut microbiota deficient mice demonstrate accelerated glucose clearance. However, which tissues are responsible for the upregulated glucose uptake remains unresolved, with different studies suggesting that browning of white adipose tissue, or modulated h
EurLex-2 Fattissue(calledadipose tissue) is more than a storage depot for triglycerides (fats). Fedtvæver imidlertid mere end blot depoter for triglycerider (fedtstoffer). jw2019
Thus, unlike white adipose tissue (WAT), BAT does not accumulate lipids just as a storage depot, but as a source of fatty acids to be oxidized in the mitochondria when BAT thermogenesis is activated in order to produce heat. Morphologically, brown adipocytes are characterized by the presence ...
These results, which were recentlypublishedinMolecular Metabolism, could contribute to the development of new therapeutic approaches for treating type 2 diabetes and obesity. White adipose tissue, once considered merely a fat storage depot, is now recognized as an endocrine organ that plays a central...
Adipose tissue demonstrates considerable plasticity and heterogeneity, enabling metabolic, cellular and structural adaptations to environmental signals. This adaptability is key for maintaining metabolic homeostasis. Impaired adipose tissue plasticity can lead to abnormal adipose tissue responses to metabolic cues...
Adipose tissue is an endocrine organ and a crucial regulator of energy storage and systemic metabolic homeostasis. Additionally, adipose tissue is a pivotal regulator of cardiovascular health and disease, mediated in part by the endocrine and paracrine secretion of several bioactive products, such as ...
Adipose tissue is comprised of a vast range of cellular and noncellular components. By volume, adipocytes are the most prominent cell within a given white fat depot. However, by cell number, it is likely that mature adipocytes are in the minority due to the presence of a large network of ...