A significant reduction of the uptake was observed when unlabeled insulin was injected together with the labeled hormone. This reduction was dose dependent, and the concentration of unlabeled insulin that prevented 50% of the tissue uptake of [ 125I]iodoinsulin was of 1 to 10 渭g/kg body ...
To examine if the augmentedMdm2expression in WAT in the obese state had physiological relevance, we generated mice lacking one allele ofMdm2in their adipose tissue, hereafter referred to asMdm2Adi+/−mice. In short, mice bearing loxP sites in theMdm2gene were crossed with mice expressing the ...
To determine the effect of sucrose intake on specific adipose tissue depots, we carefully dissected out and weighed both subcutaneous (iWAT) and visceral (gWAT) depots (Supplementary Fig.1a). No effect of sex was observed for either inguinal (p = 0.731) or gonadal (p = 0.084) adip...
BACKGROUND: Adipose tissue-derived stem cells (ADSCs) are promising for clinical application in cardiovascular cellular therapy.In vivo MR imaging of magnetically labeled ADSCs to track the survival and migration of implanted cells is important for clinical application and scientific research.However,to...
Therefore, the increased expression of CD36 and CD106 in O-ADSCs could contribute to fatty acid uptake and inflammation in obese adipose tissue. In addition, our results have shown that L-ADSCs inhibit pro-inflammatory M1 type macrophage polarization and promote anti-inflammatory M2 type ...
Schematic drawing of the experimental configuration (upper panel). Bottom panel: tdTomato-positive neurons in the DMH (left) and Rpa (right). Scale bars: 100 μm, 50 μm (inset). C and D. Images of fluorescence confocal microscopy showing tdTomato-labeled serotonergic neurons in the Rpa ...
Adipose tissue-derived stem cells (ASCs) have shown promise in cell therapy because of their ability to self-renew damaged or diseased organs and easy harvest. To ensure the distribution and quantification of the ASCs injected from tail vein, several whole-body imaging techniques including ...
The distribution of labeled palmitic acid into the diglycerides and triglycerides of rat adipose tissueAfter in vitro incubation of rat epididymal fat pads with radioactive palmitic acid, the distribution of the label in the different lipid classes and in different triglycerides was determined by ...
The objective of the study was to identify associations of longitudinal trajectories of traditional cardiometabolic risk factors with abdominal and ectopic adipose tissue depots measured by magnetic resonance imaging (MRI). We measured total abdominal, v
(Fig.1a). The fibers appear thick and suitable for cell adhesion allowing its spreading to establish good contact with the biomolecules present in the matrix. The chance of seeded cells contacting the tissue culture polystyrene (TCPS) surface seemed doubtful because of the uniform spreading of ...