We identify multiple types of adipocyte progenitors that are common across depots, including a subtype enriched in individuals with type 2 diabetes. Depot-specific analysis reveals a class of adipocyte progenitors unique to visceral adipose tissue, which shares common features with beige pre-adipocytes....
Adipose tissue is an abundant source of various cell types. Being derived from the mesenchyme, it contains not only adipocytes (well differentiated cells that cannot divide [1]), but also progenitor and endothelial cells from the stroma. Adipose tissue is an endocrine organ that releases numerous...
cell See all related content adipose cell, connective-tissuecellspecialized to synthesize and contain large globules offat. There are two types of adipose cells:white adipose cells contain large fat droplets, only a small amount ofcytoplasm, and flattened, noncentrally locatednuclei; andbrown adipose...
21.1Adipose Tissue Adipose tissue, a specialized type of connective tissue, consists of a number of different cell types such as adipocytes,endothelial cells, and macrophages. It was traditionally recognized for its ability to store excess energy and to provide insulation and padding to the body. ...
Adipose tissue, connective tissue consisting mainly of fat cells (adipose cells, or adipocytes), specialized to synthesize and contain large globules of fat, within a structural network of fibres. It is found mainly under the skin but also in deposits be
Excess adiposity can induce adverse sequelae in multiple cell types and organ systems. The transition from the lean to the obese state is characterized by fundamental cellular changes at the level of the adipocyte. These changes affect the local microenvironment within the respective adipose tissue but...
Conventional and imaging flow cytometry were used to define immune cell populations in biopsy specimens of psoriatic adipose tissue (n = 30) including T cells, B cells, NK cells, NKT cells, neutrophils, and macrophages. Relationships between adipose immune cell types and body mass index were dete...
The secretory function of adipocytes in the physiology of white adipose tissue. J. Cell. Physiol. 216, 3–13 (2008). Article CAS PubMed Google Scholar Choi, C. H. J. & Cohen, P. Adipose crosstalk with other cell types in health and disease. Exp. Cell Res. 360, 6–11 (2017). ...
Although RAGE mRNA is highly expressed in adipocytes, ATMs, and other adipose tissue cell types the role(s) of RAGE in obesity-associated inflammation and insulin resistance is unclear. Methylglyoxal (MGO) is one of the most potent glycating agents and a major precursor of AGEs [12,14]. In...