2A, B). Markers for epithelial-to-mesenchymal transition (EMT) including Wilms’ tumor 1 (WT1), and the mesenchymal marker alpha-smooth-muscle actin (α-SMA) emerged after proliferation onset in carrier aggregates (Supplementary Fig. 3A). In vivo, light-sheet and confocal images confirmed ...
Adhesion to the extracellular matrix persists during mitosis in most cell types. However, while classical adhesion complexes, such as focal adhesions, do and must disassemble to enable mitotic rounding, the mechanisms of residual mitotic cell–extracellular matrix adhesion remain undefined. Here, we ide...
The 1-year posttreatment POSAS scores for the color, pain, pruritus, hardness, fullness, mobility, and appearance of the scar were significantly decreased compared with the pretreatment scores. Hematoxylin-eosin staining revealed adipocyte-like cells in treated scar tissue specimens obtained 1 year ...
In a self-limiting fashion, multiple other stab wounds were found at the left pectoralis major muscle, forming a small but appreciable hematoma. In addition, multiple scattered foci of soft tissue gas were within the anterior chest and abdominal walls. Download: Download high-res image (247KB)...
Forough, R. et al., “Generating Antibodies Against Secreted Proteins Using Vascular Smooth Muscle Cells Transduced with Replication-Defective Retrovirus” BioTechniques, 1996, 20:694-701. Khokha, R. et al., “Antisense RNA—Induced Reduction in Murine TIMP Levels Confers Oncogenicity on Swiss 3T...
Similarly, in orthopedic surgery, placing the high pH side of a membrane against a fixed tissue, such as bone or periosteum, will cause it to adhere more firmly to those locations and permit a less fixed tissue, such as a ligament, tendon, or muscle, to move more freely. ...
The ability of cells to convert mechanical cues, sourced from the surrounding environment, into intracellular biochemical signals is of primary importance in a mechanically active tissue, such as myocardium, in which coordinated muscle contraction depends on proper mechanical and electrical coupling [3]....
The method comprises administering to a patient in need thereof a therapeutically effective amount of at least one COX-2 inhibitor, wherein the COX-2 inhibitor is not nimesulide. [0023] The present invention can also be applied to the treatment, prevention, or minimization of keloid formation,...
Ellis H. (1983). Prevention and treatment of adhesions.Infect Surg. 803–818. Google Scholar Filmar S, Jetha N, McComb P, Gomel V. (1989a). A comparative histologic study on the healing process after tissue transection. I. Carbon dioxide laser and electromicrosurgery.Am J Obstet Gynecol16...
All three abnormalities have similarities to scar tissue: adhesions are fibrous bands of scar tissue that can form after surgery or other trauma; keloids result from a localized overproduction of scar tissue; and restenosis is caused by the proliferation of smooth muscle cells after cardiovascular ...