Cell adhesion is such a mechanism by which cells adhere to themselves and with other cells with the help of cell surface proteins. The contact can either be direct like in cell junction or it can be indirect in which cells are connected by extracellular matrix adhesion. It is a gel-like m...
a The S. epidermidis altE gene is regulated by agr¸ whereas the homologous gene in S. aureus is controlled by sarA. View article Cell Adhesion and the Extracellular Matrix In Medical Cell Biology (Third Edition), 2008 CELL ADHESION HAS MANY IMPORTANT ROLES IN TISSUE FUNCTION To this point...
The meaning of CELL ADHESION MOLECULE is any of various molecules (such as cadherins, integrins, and selectins) on the surface of a cell that bring about adhesion by binding to molecules on the surface of other cells or on extracellular material —abbrev
Endothelial ICAM-1 has been reported to contribute to tumor cell adhesion to the endothelium, considering that tumor adherence to vessel walls is a general aspect; suggest that this is an incredibly important molecule (Gassmann et al., 2010). During metastasis, upregulated level of ICAM-1 was ...
A cell-surface sialoglycoprotein encoded by VCAM1 on 1p32-p31, which belongs to the Ig superfamily, is expressed by cytokine-activated endothelium, and is involved in early inflammation. It mediates leukocyte-endothelial cell adhesion and signals transduction, recruiting monocytes and lymphocytes to ...
S10A). It is noteworthy that, upon cholesterol addition, the relative cell numbers in T47D:dKO:CLDN4:LXRβS432A cells were also significantly elevated, and the increased level was similar to that in T47D:dKO:CLDN4:LXRβ cells (Additional file 1: Fig. S10B), suggesting that the CLDN4...
The term “inhibit,” as used herein, refers to the ability of a compound, agent, or method to reduce or impede a described function, level, activity, rate, etc., based on the context in which the term “inhibit” is used. Preferably, inhibition is by at least 10%, more preferably ...
The epithelial cell adhesion molecule (EpCAM) has first been described in 1979 as a humoral antigen expressed on colon carcinoma cells [1]. Here, we have summarized the impressive progress in the biology of EpCAM in the past four decades. Expression patterns, regulation, and the multiple funct...
The highest level of coumarins was detected in alcoholic extracts—methanolic <1 to 161.22 mg CE/g, ethanolic 11.22 to 126.53 mg EC/g—while aqueous extracts had the lowest amount of coumarins (<1–97.96 mg CE/g) (Figure 1). The methanolic extract of T. montanum contained the highest ...
The human intestinal epithelial Caco-2 cells (FH0029, passage 10~20) were obtained from FuHeng Biology (Shanghai, China) and cultured in Dulbecco’s modified Eagle medium (DMEM) containing 10% fetal bovine serum (FBS), 1.25% L-glutamine, and 1.25% penicillin-stretomycin solution in a humi...