ADH is a zinc-containing enzyme that consists of two protein subunits (dimeric enzyme). ADH can oxidize endogenous ethanol produced by microorganisms in the gut as well as consumed ethanol. ADH has broad substrate specificity and can metabolize primary as well as secondary alcohol, such as methano...
Since "phasic" neurones have been identified as ADH-secreting neurones, it is concluded that ADH-secreting neurones in the rat supraoptic nucleus receive predominantly excitatory synaptic inputs from the medial amygdala and these amygdalar synaptic inputs are mediated by pathways which are at least...