Cardioprotective Actions of Adenosine in the Heart: New Strategy for the Treatment of Ischemic Heart Diseases5’-Nucleotidase5’-AMPATP-sensitive K+ channelMyocardial stunningMyocardial necrosisIschemic preconditioningAdenosine is recognized as an important chemical mediator for myocardial and vascular functions...
Role of adenosine in the heart and circulation. 来自 Semantic Scholar 喜欢 0 阅读量: 52 作者:Mubagwa,Mullane,Flameng 摘要: Author information: (1)Centre of Experimental Surgery and Anaesthesiology, Katholieke Universiteit Leuven, Belgium.
The effect of age on adenosine A1 receptor function in the rat heart. Adenosine is an important regulatory metabolite in the heart where it has a cardioprotective function. In the ventricle, the cardioprotective action of ade... E Gao,DL Snyder,MD Johnson,... - 《Journal of Molecular & Cel...
ATP may, therefore, have an important role to play in the initiation of hypoxic dilatation which is mediated by the release of endothelium-derived relaxing factor. 展开 关键词: Hypoxia Heart ATP Adenosine Endothelium-derived relaxing factor (EDRF ...
Release of adenosine and lactate from the heart during atrial pacing in patients with coronary stenosisAuthor links open overlay panelTakashi Haneda, Kazuo Ichihara, Sokichi Onodera, Yasushi AbikoShow more Add to Mendeley Share Cite https://doi.org/10.1016/S0021-5198(19)59037-0Get rights and ...
Modulation of the myocardial adenosine system and its signaling pathways may be a novel therapeutic target in patients with heart failure. 调节心肌腺苷系统和它的信号途径可能是兴衰病人治疗的新途径。 www.med66.com 3. Cells of the immune system express these receptors and are responsive to the modul...
Hyperthyroidism induces a number of metabolic and physiological changes in the heart including hypertrophy, increase in inotropic status, and alterations of myocardial energy metabolism. The effects of hyperthyroidism on adenosine metabolism which is intimately involved in the control of many aspects of myo...
1. Adenine can promote leukocyte proliferation in the body in medical applications and increase the number of white blood cells. In addition, it also helps regulate the heart rate, relieves fatigue, and strengthens the body's immune function. It can be used for tumor radiation therapy and tumor...
Recently, adenosine has been demonstrated to play a critical role in protecting the embryo against hypoxia via adenosine A1 receptors (A1ARs), which are expressed in the heart, nervous system, and other sites during development. However, the sites of A1AR action that mediate embryo protection ...
We therefore investigated whether myocardial adenosine receptor activation (and which of its subtypes) would play a role in IPC in the rat heart when longer IPC stimuli are employed. The concept of ischemic preconditioning (intraorgan protection) has been expanded to interorgan preconditioning (IOPC...