The calcium-activated chloride channel (CLCA4) in colon adenocarcinoma (COAD) and immunological infiltration have not been extensively studied. This work thoroughly employed several datasets to assess the expression, prognosis, and association between immune infiltration and clinicopathologic...
This subtype of adenocarcinoma has distinctly poor prognosis in the early stage compared with other subtypes of adenocarcinoma.18–20 Solid Adenocarcinoma The tumor cells form patternless sheets and lack any other recognizable patterns, including poorly differentiated/undifferentiated carcinomas expressing ...
No significant correlation between NPM3 expression and the pathological stage was observed in other cancer types [Supplementary Figure 2]. In addition, we analyzed the protein expression of NPM3 using immunohistochemistry (IHC) data from the HPA database and compared it with NPM3 RNA differential ...
Prognosis of Signet Ring Cell Carcinoma of the Colon and Rectum and their Distinction of Mucinous Adenocarcinoma with Signet Ring Cells. A Comparative Study Histological subtype plays an important role in the different clinical characteristics and survival outcomes of patients with colorectal carcinoma (CR...
Lung adenocarcinoma (LUAD) is one of the sole causes of death in lung cancer patients. This study combined with single-cell RNA-seq analysis to identify tumor stem-related prognostic models to predict the prognosis of lung adenocarcinoma, chemotherapy ag
Lung cancer remains the primary cause of cancer-related deaths globally, with lung adenocarcinoma (LUAD) being its most dominant histological subtype1,2. Despite considerable progress in therapeutic approaches for LUAD, particularly with the introduction of immunotherapy, the prognosis remains less than...
In this study, we aimed to evaluate the expression of HIF-1α in colon adenocarcinoma and to explore its clinicopathological characteristics and prognosis. A tissue microarray involving colon adenocarcinoma tissues and their corresponding paracancerous tissues from 92 patients was utilized to detect HIF...
Single-cell analyses inform mechanisms of myeloid-targeted therapies in colon cancer. Cell 181, 442–459.e29 (2020). Article CAS PubMed Google Scholar Cui Zhou, D. et al. Spatially restricted drivers and transitional cell populations cooperate with the microenvironment in untreated and chemo-...
Colon cancer is the third most common cancer and second highest cause of cancer deaths worldwide. The aim of the study was to find new biomarkers for diagnosis, prognosis and therapeutic drug targets for this disease. Four low-grade and four high-grade h
High-throughput proteomics profiling-derived signature associated with chemotherapy response and survival for stage II/III colorectal cancer Article Open access 31 May 2023 EPYC functions as a novel prognostic biomarker for pancreatic cancer Article Open access 06 January 2024 Proteomic characterization...