Metastasis is the major cause of treatment failure in patients with prostate adenocarcinoma (PRAD). Diverse programmed cell death (PCD) patterns play an important role in tumor metastasis and hold promise as predictive indicators for PRAD metastasis. Usi
Previous studies have suggested that β-adrenergic signaling may regulate the growth of various cancers. The aim of our study is to investigate the association between the incidental use of beta-blockers for various conditions on the overall survival of
The EPIC cohort The EPIC study has been fully described elsewhere [24,25,26]. Briefly, EPIC is one of the largest prospective cohort studies in Europe. It recruited 521,323 participants between 1992 and 2000. Participants were enrolled in 23 centres across 10 European countries, namely Denmark...
We identified colorectal cancer patients newly registered into the TCDB according to ICD-O-3 (International Classification of Diseases for Oncology, third revision) code C18.0 (cecum)-C21.8 (rectum). Exclusion criteria included patients with stage IV, cancer at anus, pathologic report beyond ...
- 《Annals of the Rheumatic Diseases》 被引量: 1发表: 2015年 Improving outcomes for New Zealand men with prostate cancer. Prostate cancer (PCa) screening to detect early stage PCa has resulted in increased identification of small-volume, low-grade PCa, many of which meet crite... JN Nacey...
1 Over 80% of patients are not candidates for surgical resection, which remains the sole potentially curative treatment. Median survival for patients diagnosed at an advanced stage ranges from 6.8-11 months to 10–24.2 months for metastatic and non-metastatic locally advanced diseases, respectively....
Moreover, PFKFB4 by reducing prostate cancer cells fructose-2,6-bisphosphate level, make the glucose-6-phosphate guide the PPP, reduces the glycolytic pathway activity, make the NADPH and glutathione levels, eventually reduce the oxidative stress and death of tumor cells, prevent prostate cancer ...
Candidate cases were identified via two parallel pathways: claims interrogation of contracted members (ICD-10 codes: C25.0–C25.9) for the prospective identification of patients OR patient request for a second opinion. The claims-based program, known as Accountable Precision Oncology (APO), runs as...
This suggests a potential paracrine effect of the PDAC, whereby potential mediators of DM, such as adrenomedullin, are locally produced by the tumour and inhibit the action of β-cells in the pancreas [10]. Overall, DM is associated with 1.5–2 fold higher risk of PDAC, compared to people...
The downregulation of miR-101 occurs through genetic and epigenetic mechanisms. Decreased miR-101 levels are associated with cancer development, progression, and poor prognosis in lung, breast, prostate, liver, bladder, gastric and colorec- tal cancer [17]. Of note, miR-101 has been found to ...