CANCER chemotherapyTREATMENT effectivenessINTESTINAL perforationBackground: Gastric adenocarcinoma with enteroblastic differentiation (GACED), a rare subtype of gastric cancer, is associated with a more aggressive behavior than conventional gastric adenocarcinomas. We report a rare case of stage IV GACED ...
NCT04514497: Testing the addition of an anti-cancer drug, BAY 1895344, to usual chemotherapy for advanced stage solid tumors, with a specific focus on patients with small cell lung cancer, poorly differentiated neuroendocrine cancer, and pancreatic cancer. https://clinicaltrials.gov/ct2/show/NCT04...
Advanced metastatic cancer poses utmost clinical challenges and may present molecular and cellular features distinct from an early-stage cancer. Herein, we present single-cell transcriptome profiling of metastatic lung adenocarcinoma, the most prevalent histological lung cancer type diagnosed at stage IV in...
today, I rang the victory bell in the Baptist Hospital Comprehensive Cancer Center. Normally patients ring the bell when their cancer regiment is complete. I rang it to celebrate my five years since being diagnosed with stage 4 pancreatic cancer. I had planned to ring it back in January. But...
Widespread prostate specific antigen (PSA) testing results in detection of prostate cancer 4–6 years earlier than possible with digital rectal examination. Twenty to thirty percent of prostate cancers detected with PSA testing (non-palpable disease) are small tumors (< 0.5cc) that may be unimporta...
International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society has led us to conduct a study of 104 patients with early-stage primary pulmonary adenocarcinoma (T1N0M0), with a view to histological subtype as defined by the new proposal and clinical ...
对于难治性或复发性宫颈腺癌，可采用盆腔脏器廓清术、全盆腔放疗或铂类为基础的姑息性化疗。【关键词】宫颈肿瘤；妇科外科手术；放射疗法；药物疗法 Treatment Progress of Cervical Adenocarcinoma WEN Qiang ，FANG Su-hua.Department of Gynecological Oncology ，Zhejiang Cancer Hospital ，Hangzhou 310022，China 【...
Overall, we find a heterogeneous mixture of basal and classical cancer cell subtypes, along with distinct cancer-associated fibroblast and macrophage subpopulations. Strikingly, classical and basal-like cancer cells exhibit similar transcriptional responses to chemotherapy and do not demonstrate a shift ...
Endoscopic stent implantation is a common short-treatment option in palliative settings in patients with esophageal cancer. Advanced disease is associated with low survival rates; therefore, data on the long-term outcome are limited. So far, cases of long-term remission or even cure of metastasized...
Tissue architecture contributes to pancreatic ductal adenocarcinoma (PDAC) phenotypes. Cancer cells within PDAC form gland-like structures embedded in a collagen-rich meshwork where nutrients and oxygen are scarce. Altered metabolism is needed for tumour