Addition of the Grignard reagent derived from bromide 8 to the isomeric bis-spiroacetal aldehydes 7b,7c,7d also afforded erythro alcohols 9b,9c,9d, respectively as the major products. A rationale for this observed stereoselectivity is provided. Attempts to effect iodoetherification of alkene 9a ...
ChemInform Abstract: STUDY OF THE STEREOCHEMISTRY OF THE ADDITION OF A GRIGNARD REAGENT TO 20-KETO-18-PREGNANOIC ACID METHYL ESTERsteroidsDurch Reaktion des Pregnan-20-ons (I) mit den entsprechenden Grignard-Reagenzien in ther entstehen die (20S)-Alkohole (II)....
摘要: Reaction of nitroalkanes with Grignard reagents, in the presence of anhydrous CeCl3 in tetrahydrofuran at –78 °C, affords N,N-disubstituted hydroxylamines in fair to good yields, depending on the nature of the reagent used.DOI: 10.1039/c39930001373 被引量: 56 ...
reactingGrignard reagents,carbonbasednucleophiles,withcarbonylsisaneffectivewayofmaking secondaryandtertiaryalcohols.Additionally,sincealcoholscanbereducedtoalkanesor convertedtootherfunctionalgroups,thereactionofaGrignardreagentwithacarbonylis anexcellentwaytoformcarbon–carbonbonds. Let’sfirstconsidertheformationofthe...
1) Grignard reagent addition 格氏加成还原2) Schardinger reductase 沙丁格尔氏还原酶3) wustite reduction 浮氏体还原 1. A study of the effects of water gas reaction on the wustite reduction; 水煤气反应对浮氏体还原影响的实验研究4) hydrogenation reduction 加氢还原 1. Preparation of p-...
Catalytic enantioselective conjugate addition of Grignard reagents to cyclic α,β-unsaturated carbonyl compounds A catalytic asymmetric conjugate addition reaction of organocopper reagents, generated from copper salt, a chiral phosphine, and Grignard reagent, with cyc... Motomu Kanai a,Yuichi Nakagawa b,...
Interactive 3D animation of a Grignard reagent reacting with an aldehyde forming an alcohol for students studying University chemistry courses
This review summarizes the recent advance in the enantioselectivity of 1,4-conjugate addition of Grignard reagents to α,β-unsaturated carbonyl compounds catalyzed by copper-complex. 铜络合物催化的有机金属试剂与α,β-不饱和羰基化合物的1,4-共轭加成反应,是形成新的C—C键的重要方法之一。 2. Rhodi...
Dimeric tert-butoxymagnesium bromide–diethyl ether adduct, [Mg2Br2(C4H9O)2(C4H10O)2]: the addition product of a Grignard reagent with acetoneFirst page of articledoi:10.1107/S0108270184005035N. A. BellP. T. MoseleyH. M. M. Shearer
A. Grignard Reagent Addition to 5-Alkylamino-4H-Imidazole 3-Oxides: Synthesis of New pH-Sensitive Spin Probes. Synthesis 2003, 871- 878.Kirilyuk IA, Shevelev TG, Morozov DA, Khromovskih EL, Skuridin NG, Khramtsov VV, Grigor’ev IA. Grignard reagent addition to 5-alkylamino- 4 H -...