[4].L. Gardner Coffman,et al.746P - Phase III MIRASOL trial:Updated overall survival results of mirvetuximab soravtansine (MIRV) vs. investigator’s choice chemotherapy (ICC) in patients (pts) with platinum-resista...
Magenta Therapeutics周二表示,根据针对复发/难治性急性髓性白血病(AML)和骨髓增生异常综合征(MDS)的MGTA-117 1/2期剂量递增临床试验的临床试验方案,它已停止对参与者进行给药队列4剂量水平(0.13 mg/kg),并计划以队列3剂量水平(0.08 mg/kg)对其他参与者进行给药。 Jas...
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Jason Gardner, Magenta Therapeutics CEO 队列4中有3例参与者接受了给药,在第二和第三次给药的参与者中观察到剂量限制性毒性(dlt)。第一名参与者完成了21天DLT观察期,无DLT发生。在该公司于2022年12月13日向投资者介绍情况之后,该公司收到报告称,队列4中的第二例参与者发生了被认为可能与MGTA-117相关的4级...
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