Successful ADCs depend on the identification of suitable targets and adequate target expression density for efficacy. FRα stands out as a promising target, with MIRV targeting FRα being the preferred regimen for FRα-positive patients with PROC. DMUC4046A, targeting MUC16, is another promising ...
ADCs offer precise delivery of cytotoxic agents, potentially overcoming chemotherapy resistance while minimizing off-target toxicities. Successful ADCs depend on the identification of suitable targets and adequate target expression density for efficacy. FRα stands out as a promising target, with MIRV targe...
The effect of current density on the microstructure and mechanical properties of cast ADC 12 recycled aluminum has here been investigated by using a pulsed electric field and a self-developed high-power pulsed device. The results showed that the pulsed electric field could refine the microstructure ...
The results showed that Ptz could be conjugated with Strand 1 at the same high conjugation efficiency as Ctx–Strand 1 (, Appendix A Supplementary material). Thus, Ptz–Strand 1 could successfully be assembled with JXW12O to form Ptz–JXW12O (, Appendix A Supplementary material). Download: ...
The cell culture flasks with the initial cell density at 730 nm (OD730) of about 0.05 were placed on the rotary shaker at 160 rpm speed. Cell growth was measured at OD730 by spectrophotometer. For nutrient-deprived conditions, all Synechocystis strains were initially grown in normal BG11 ...
The density of the epidermal nerve fibers was analyzed by counting the numbers of nerve fibers per 0.3 mm of epidermis. Nerve fibers branching in zone 2 were counted separately, while nerve fibers branching in zone 3 were counted as one. Simultaneous RNAscope and immunofluorescence assay To ...
For example, system designers are forced to make performance trade-offs to keep a tight system power budget or small area on the board to achieve high channel density. System designers of these precision data acquisition signal chains face common challenges in terms of driving the SAR A...
enabling higher channel density X Breaks barrier of ODR being a function of the sampling clock X Gives independent control of interface to external digital controller X Improves the signal chain reliability rating, which is a direct result of periphery component reduction X Reduces size and has a ...
ADC3224 (fS = 125 MSPS) DITHER ON PARAMETER TEST CONDITIONS MIN TYP DITHER OFF MAX MIN TYP MAX UNIT DYNAMIC AC CHARACTERISTICS fIN = 10 MHz fIN = 70 MHz Signal-to-noise ratio (from 1-MHz offset) SNR Signal-to-noise ratio (full Nyquist band) 68.5 Noise spectral density (averaged ...
unless otherwise noted PARAMETER TEST CONDITIONS MIN TYP MAX UNIT NSD Noise Spectral Density SNR Signal to noise ratio SINAD Signal to noise and distortion ratio ENOB Effective number of bits THD Total Harmonic Distortion (First five harmonics) HD2 Second Harmonic Distortion HD3 Third Harmonic Distorti...