Adaptor proteins 在细胞信号转导中发挥着关键作用。细胞外的信号分子与细胞膜上的受体结合后,adaptor proteins 可以帮助受体与其他信号分子或酶结合,从而引发一系列的细胞内信号传递事件。Adaptor proteins 还可以参与细胞内细胞器之间的物质运输和分子传递。 此外,adaptor proteins 在细胞增殖、凋亡、代谢等生物学过程中也...
Adaptor proteins play key roles in cellular signaling such as phosphorylation, dephosphorylation, signal transduction, organization of the cytoskeleton, cell adhesion, regulation of gene expression, all distinct yet interacting systems. Proteins equipped with the Rous sarcoma oncogen (Src) homology domains ...
网络释义 1. 接头蛋白 分子细胞生物学 ... ... 异嗜性粘着 heterophilic adhesion接头蛋白adaptor proteins效应蛋白 effector proteins ... blog.sina.com.cn|基于2个网页 2. 适配体蛋白 ...ases的凋亡机制 • 通过线粒体途径的调控;通过适配体蛋白(adaptor proteins)直接传递信号途径的 调控;粒酶B途径的调...
adaptor proteinsdocking proteinsintracellular signallingscaffold proteinsSH2 domainSH2D2ATSAdTo maintain homeostasis, all cells respond to environmental cues via a multitude of surface receptors. In order to act appropriately in their environment, cells are dependent on the transduction of the incoming ...
Definition Adaptor proteins are cell signaling molecules linking intracellular proteins, including cell surface receptors to cytosolic effectors.DefinitionAdaptor proteins are cell signaling molecules linking intracellular proteins, including cell surface receptors to cytosolic effectors.Characteristics In their pure...
The ubiquitin ligases c-Cbl and Cbl-b play a crucial role in receptor downregulation by mediating multiple monoubiquitination of receptors and promoting their sorting for lysosomal degradation. Their function is modulated through interactions with regulatory proteins including CIN85 and PIX, which recognize...
Adaptor proteins in protein kinase C-mediated signal transduction. Oncogene 20: 6339 - 6347, 2001.Schechtman, D, Mochly-Rosen, D (2001) Adaptor proteins in protein kinase C-mediated signal transduction. Oncogene 20: pp. 6339-6347Schechtman D, Mochly-Rosen D (2001) Adaptor proteins in protein...
adaptor proteins had been implicated in a variety of human diseases. Therefore, creating a precise model to predict the function of adaptor proteins is one of the vital tasks in bioinformatics and computational biology. Few computational biology studies have been conducted to predict the protein ...
Here we show that WIP interacts with endocytic adaptor proteins of the intersectin (ITSN) family, ITSN1 and ITSN2. The interaction is mediated by the SH3 domains of ITSNs and the middle part of the WIP proline-rich motifs. We have also demonstrated that ITSN1, WIP and N-WASP can ...
Differential Regulation of Clathrin and Its Adaptor Proteins during Membrane Recruitment for Endocytosis Y, Sanchez-Rodriguez C, Gadeyne A, et al (2016) Differential regulation of clathrin and its adaptor proteins during membrane recruitment for endocytosis. ... Persson,Staffan,Bednarek,... 被引量:...