In the table, KM and Vmax values ± errors were obtained by non-linear least squares fitting to the Michaelis-Menten equation. Bottom panel shows individual degradation rates. Source data Supplementary information Supplementary Information Supplementary Table 1, Figs. 1–7, references and unprocessed ...
in the development of rat hippocampal neurons. We found that the loss of AP-2 during the early stage of development resulted in impaired axon extension and failed maturation of the axon initial segment (AIS). Normally the AIS performs two tasks in concert, stabilizing neural polarity and generat...
Vertical axis, normalized sedimentation pattern, g(S*)/Co; horizontal axis: apparent sedimentation coefficient, S*. The slight shift (arrow) to higher S* values may reflect a very weak self-association under these conditions. However, global fitting of these data to a single species model did...