Question 10. How can I predict my patient’s ADAMTS13 activity in order to decide whether to initiate plasma exchange if the results of an ADAMTS13 activity test are not yet available? References 1. Masias C, Cataland SR. The role of ADAMTS13 testing in the diagnosis and management of thr...
Does ADAMTS13 digest VWF multimers on the surface of the platelet thrombus or is thrombus size attenuation by ADAMTS13 independent of its VWF-cleaving activity? In this context, it is certainly intriguing that the mechanism of VWF size regulation by ADAMTS13 might be different from that of VWF...